Investigating fine and gross motor deficits in pediatric patients off therapy for acute lymphoblastic leukemia
Language English Country Great Britain, England Media print-electronic
Document type Journal Article
PubMed
40083148
PubMed Central
PMC11912241
DOI
10.1080/07853890.2025.2477292
Knihovny.cz E-resources
- Keywords
- Bruininks-Oseretsky test of motor proficiency (BOT-2 CF), Paediatric acute lymphoblastic leukaemia (ALL), motor performance deficits, motor skills assessment, rehabilitation in paediatric oncology,
- MeSH
- Precursor Cell Lymphoblastic Leukemia-Lymphoma * physiopathology complications drug therapy MeSH
- Child MeSH
- Humans MeSH
- Adolescent MeSH
- Young Adult MeSH
- Motor Skills * physiology MeSH
- Motor Skills Disorders * diagnosis etiology MeSH
- Child, Preschool MeSH
- Check Tag
- Child MeSH
- Humans MeSH
- Adolescent MeSH
- Young Adult MeSH
- Male MeSH
- Child, Preschool MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Geographicals
- Czech Republic MeSH
PURPOSE: To assess motor performance among Czech paediatric off therapy patients of acute lymphoblastic leukaemia (ALL) and to compare their data with normative data. METHODS: Thirty-nine off therapy patients (21 girls, 18 boys; aged 4-21 years) were evaluated using the Complete Form of the Bruininks-Oseretsky Test Second Edition (BOT-2 CF) approximately 1.5 years post-therapy cessation. Gross and fine motor skills were assessed. Normative data from BOT-2 CF served as the basis for comparison. RESULTS: The total motor composite (p = .381, Cohen's d = 0.14) and overall fine (p = .743; Cohen's d = 0.05) and gross (p=.312; Cohen's d = 0.16) motor performance were similar to the normative data. Motor deficits in manual coordination (p = .018; Cohen's d = 0.45), strength and agility (p = .012; Cohen's d = 0.51), manual dexterity (p < .001; Cohen's d = 0.59) and running speed and agility (p < .001; Cohen's d = 0.97) were identified, along with performance better than the established norms on fine motor integration (p = .048; Cohen's d = 0.33) and bilateral coordination (p = .018; Cohen's d = 0.47). CONCLUSION: The findings suggest nuanced motor skill outcomes in ALL off therapy patients, with both deficits and strengths observed. Comprehensive assessments are vital for tailoring rehabilitation strategies to address the varied impacts of ALL and its treatment on motor skills.
3rd Faculty of Medicine Charles University Prague Czech Republic
Edson College of Nursing and Health Innovation Arizona State University Phoenix Arizona USA
Institute for the Care of Mother and Child Prague Czech Republic
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