Pemetrexed [pemetrexed]
- Terms
-
Alimta
pemetrexed disodium
-
Alimta
LY 231,514
LY 231514
LY-231,514
LY-231514
LY231514
MTA
N-(4-(2-(2-amino-3,4-dihydro-4-oxo-7H-pyrrolo(2,3-d)pyrimdin-5-yl)ethyl)benzoyl)glutamic acid
Pemetrexed Disodium
A guanine-derived ANTINEOPLASTIC AGENT that functions as a NUCLEIC ACID SYNTHESIS INHIBITOR through its binding to, and inhibition of, THYMIDYLATE SYNTHASE.
- DUI
- D000068437 MeSH Browser
- CUI
- M0227083
- CAS
- L-Glutamic acid, N-(4-(2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo(2,3-d)pyrimidin-5-yl)ethyl)benzoyl)-
- History note
- 2016 (1994)
- Public note
- 2016; PEMETREXED was indexed under GLUTAMATES 1994-2015, and under GUANINE 1994-2015
Allowable subheadings
- AD
- administration & dosage 20
- AE
- adverse effects 16
- AG
- agonists 0
- AA
- analogs & derivatives 0
- AN
- analysis 0
- AI
- antagonists & inhibitors 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 1
- CL
- classification 0
- EC
- economics 1
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 0
- PK
- pharmacokinetics 2
- PD
- pharmacology 9
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 40
- TO
- toxicity 0
- UR
- urine 0