MutL Proteins [MutL proteiny]

topical
Terms

homolog MutL
homology MutL
MutL homolog

 

MutL Homologs

Persistent link   https://www.medvik.cz/link/D000070956
Definition

DNA repair proteins that include the bacterial MutL protein and its eukaryotic homologs. They consist of a conserved N-terminal region with weak ATPase activity, an endonuclease motif, and a C-terminal domain that forms MutL homodimers or heterodimers between MLH1 and the PMS1, MISMATCH REPAIR ENDONUCLEASE PMS2; or MLH3 proteins. These complexes function in DNA repair pathways, primarily DNA MISMATCH REPAIR, where MutL/MLH1 and the MUTS DNA MISMATCH-BINDING PROTEIN are targeted to damaged DNA.

DUI
D000070956 MeSH Browser
CUI
M000612744
Previous indexing
Adenosine Triphosphatases (1992-2016); DNA Repair (1982-2016)
History note
2017
Public note
2017

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D08 Enzymes and Coenzymes 7
D08.811 Enzymes 1 554
D08.811.074 DNA Repair Enzymes 61
D08.811.074.062 AlkB Enzymes
D08.811.074.124 Deoxyribodipyrimidine Photo-Lyase 1
D08.811.074.249 DNA Glycosylases 19
D08.811.074.500 DNA Ligases 6
D08.811.074.750 DNA-(Apurinic or Apyrimidinic Site) Lyase 9
D08.811.074.766 MutL Proteins
D08.811.074.766.250 Mismatch Repair Endonuclease PMS2 8
D08.811.074.766.500 MutL Protein Homolog 1 17
D08.811.074.844 MutS Proteins
D08.811.074.875 Polynucleotide 5'-Hydroxyl-Kinase 2
D08.811.277 Hydrolases 475
D08.811.277.040 Acid Anhydride Hydrolases 6
D08.811.277.040.025 Adenosine Triphosphatases 429
D08.811.277.040.025.024 ATPases Associated with Diverse Cellular Activities 8
D08.811.277.040.025.047 Arsenite Transporting ATPases
D08.811.277.040.025.095 Ca(2+) Mg(2+)-ATPase 18
D08.811.277.040.025.142 Chaperonins 9
D08.811.277.040.025.159 DNA Helicases 64
D08.811.277.040.025.176 Mi-2 Nucleosome Remodeling and Deacetylase Complex 2
D08.811.277.040.025.193 Molecular Motor Proteins 11
D08.811.277.040.025.215 MutL Proteins
D08.811.277.040.025.215.250 Mismatch Repair Endonuclease PMS2 8
D08.811.277.040.025.215.500 MutL Protein Homolog 1 17
D08.811.277.040.025.292 MutS Proteins
D08.811.277.040.025.314 P-type ATPases
D08.811.277.040.025.325 Proton-Translocating ATPases 28
D08.811.277.040.025.494 SecA Proteins 2
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 584
D12.776.260 DNA-Binding Proteins 563
D12.776.260.060 Adenovirus E2 Proteins 1
D12.776.260.103 Basic Helix-Loop-Helix Transcription Factors 65
D12.776.260.108 Basic-Leucine Zipper Transcription Factors 18
D12.776.260.114 Butyrate Response Factor 1
D12.776.260.120 CCCTC-Binding Factor 2
D12.776.260.123 Centromere Protein A 2
D12.776.260.125 Centromere Protein B
D12.776.260.158 Early Growth Response Transcription Factors 1
D12.776.260.197 Elongin
D12.776.260.235 Erythroid-Specific DNA-Binding Factors 1
D12.776.260.246 Factor For Inversion Stimulation Protein
D12.776.260.254 G-Box Binding Factors
D12.776.260.257 GATA Transcription Factors 2
D12.776.260.260 Heat Shock Transcription Factors 1
D12.776.260.262 Hepatocyte Nuclear Factors 5
D12.776.260.268 Heterogeneous-Nuclear Ribonucleoprotein K
D12.776.260.312 HMGA Proteins 1
D12.776.260.356 HMGB Proteins 4
D12.776.260.400 Homeodomain Proteins 128
D12.776.260.420 I-kappa B Proteins 5
D12.776.260.457 Immunoglobulin J Recombination Signal Sequence-Binding Protein
D12.776.260.495 Integration Host Factors
D12.776.260.504 Interferon Regulatory Factors 11
D12.776.260.513 Interferon-Stimulated Gene Factor 3
D12.776.260.522 Kruppel-Like Transcription Factors 26
D12.776.260.525 Ku Autoantigen 5
D12.776.260.527 Leucine-Responsive Regulatory Protein
D12.776.260.529 LIM-Homeodomain Proteins 5
D12.776.260.531 Liver X Receptors 6
D12.776.260.532 Matrix Attachment Region Binding Proteins 9
D12.776.260.534 MDS1 and EVI1 Complex Locus Protein 2
D12.776.260.536 Methyl-CpG-Binding Protein 2 12
D12.776.260.538 Minichromosome Maintenance 1 Protein 1
D12.776.260.539 MRE11 Homologue Protein 8
D12.776.260.540 MutL Proteins
D12.776.260.540.250 Mismatch Repair Endonuclease PMS2 8
D12.776.260.540.500 MutL Protein Homolog 1 17
D12.776.260.556 MutS Proteins
D12.776.260.560 Myeloid-Lymphoid Leukemia Protein 39
D12.776.260.600 NF-kappa B 222
D12.776.260.605 NFI Transcription Factors 9
D12.776.260.615 Nuclear Respiratory Factors
D12.776.260.623 Nucleobindins 3
D12.776.260.630 Oncogene Protein p55(v-myc) 1
D12.776.260.640 Origin Recognition Complex 1
D12.776.260.643 Orphan Nuclear Receptors 2
D12.776.260.645 Paired Box Transcription Factors 21
D12.776.260.650 Peptidyl-Prolyl Cis-Trans Isomerase NIMA-Interacting 4
D12.776.260.655 POU Domain Factors 4
D12.776.260.660 Proto-Oncogene Proteins c-bcl-6 3
D12.776.260.665 Proto-Oncogene Proteins c-ets 19
D12.776.260.675 Proto-Oncogene Proteins c-myb 31
D12.776.260.682 Proto-Oncogene Proteins c-rel 2
D12.776.260.690 Proto-Oncogene Proteins c-sis 3
D12.776.260.693 PTB-Associated Splicing Factor
D12.776.260.695 Rad51 Recombinase 43
D12.776.260.696 Rad52 DNA Repair and Recombination Protein 9
D12.776.260.700 Replication Protein A 12
D12.776.260.702 Replication Protein C 3
D12.776.260.703 Repressor Proteins 189
D12.776.260.704 Retinoblastoma Protein 52
D12.776.260.713 Smad Proteins 14
D12.776.260.716 SMARCB1 Protein 15
D12.776.260.719 SOX Transcription Factors 1
D12.776.260.725 T-Box Domain Proteins 14
D12.776.260.730 TCF Transcription Factors 3
D12.776.260.733 TEA Domain Transcription Factors 3
D12.776.260.735 Telomere-Binding Proteins 25
D12.776.260.750 Toll-Like Receptor 9 16
D12.776.260.755 Trans-Activators 111
D12.776.260.760 Transcription Factor AP-2 1
D12.776.260.768 Transcription Factor MTF-1
D12.776.260.775 Transcription Factors, General 1
D12.776.260.790 Tristetraprolin 2
D12.776.260.805 Tumor Suppressor p53-Binding Protein 1 16
D12.776.260.820 Tumor Suppressor Protein p53 767
D12.776.260.885 Tumor Protein p73 6
D12.776.260.950 Winged-Helix Transcription Factors
D12.776.260.963 X-ray Repair Cross Complementing Protein 1 9
D12.776.260.975 Xeroderma Pigmentosum Group A Protein 2

MLH2 protein, S cerevisiae Chemical MeSH Browser

MLH3 protein, S cerevisiae Chemical MeSH Browser

MLH3 protein, human Chemical MeSH Browser

Mlh3 protein, mouse Chemical MeSH Browser

Mlh3 protein, rat Chemical MeSH Browser

MutL protein, E coli Chemical MeSH Browser

MutLalpha protein, human Chemical MeSH Browser

PMS1 protein, Arabidopsis Chemical MeSH Browser

PMS1 protein, S cerevisiae Chemical MeSH Browser

PMS1 protein, human Chemical MeSH Browser

PMS1 protein, mouse Chemical MeSH Browser

PMS1 protein, rat Chemical MeSH Browser

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