ERG1 Potassium Channel [draslíkový kanál ERG1]
- Terms
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draslíkové kanály řízené napětím, člen 2 podrodiny H
draslíkový kanál ether-a-go-go 1
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Ether-A-Go-Go-Related Potassium Channel 1
Kv11.1 Protein-Potassium Channel
Potassium Voltage-Gated Channel, Subfamily H, Member 2
One of three members of the ether-a-go-go (EAG) POTASSIUM CHANNELS gene family comprising ether-a-go-go (eag), eag-like (elk) and eag-related (erg) subfamilies. Ether-a-go-go-related gene 1 (ERG1) also known as KCNH2, encodes the pore-forming subunit of a rapidly activating-delayed rectifier potassium channel that plays an essential role in the final repolarization of ventricular action potential. Loss-of-function mutations in human hERG1 is associated with life-threatening ARRHYTHMIA.
- DUI
- D000072237 MeSH Browser
- CUI
- M0386712
- History note
- 2017 (2001)
- Public note
- 2017; ERG1 POTASSIUM CHANNEL was indexed under POTASSIUM CHANNELS, VOLTAGE-GATED 2005-2008, and under ETHER-A-GO-GO POTASSIUM CHANNELS 2009-2016
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