ERG1 Potassium Channel [draslíkový kanál ERG1]
- Terms
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draslíkové kanály řízené napětím, člen 2 podrodiny H
draslíkový kanál ether-a-go-go 1
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Ether-A-Go-Go-Related Potassium Channel 1
Kv11.1 Protein-Potassium Channel
Potassium Voltage-Gated Channel, Subfamily H, Member 2
One of three members of the ether-a-go-go (EAG) POTASSIUM CHANNELS gene family comprising ether-a-go-go (eag), eag-like (elk) and eag-related (erg) subfamilies. Ether-a-go-go-related gene 1 (ERG1) also known as KCNH2, encodes the pore-forming subunit of a rapidly activating-delayed rectifier potassium channel that plays an essential role in the final repolarization of ventricular action potential. Loss-of-function mutations in human hERG1 is associated with life-threatening ARRHYTHMIA.
- DUI
- D000072237 MeSH Browser
- CUI
- M0386712
- History note
- 2017 (2001)
- Public note
- 2017; ERG1 POTASSIUM CHANNEL was indexed under POTASSIUM CHANNELS, VOLTAGE-GATED 2005-2008, and under ETHER-A-GO-GO POTASSIUM CHANNELS 2009-2016
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 1
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology 1
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 1
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
ERG1 A protein, mouse Chemical MeSH Browser
ERG1 B protein, mouse Chemical MeSH Browser
KCNH2 protein, human Chemical MeSH Browser
Kcnh2 protein, mouse Chemical MeSH Browser
Kcnh2 protein, rat Chemical MeSH Browser