Wortmannin [wortmannin]
topical
- Terms
-
MS 54
MS-54
Persistent link
https://www.medvik.cz/link/D000077191
Definition
An androstadiene metabolite produced by the fungi PENICILLIUM funiculosum that inhibits PHOSPHATIDYLINOSITOL-3-KINASES and alloantigen-specific activation of T-LYMPHOCYTES in human tumor cell lines. It is widely used in CELL BIOLOGY research and has broad therapeutic potential.
- DUI
- D000077191 MeSH Browser
- CUI
- M0054588
- CAS
- (1 alpha,11 alpha)-11-(Acetyloxy)-1-(methoxymethyl)-2-oxaandrosta-5,8-dieno(6,5,4-bc)furan- 3,7,17-trione
- History note
- 2019 (1974)
- Public note
- 2019; WORTMANNIN was indexed under ANDROSTADIENES 1980-2018, and under COUMARINS and INDENES 1974-1979
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AA
- analogs & derivatives
- AN
- analysis
- AI
- antagonists & inhibitors
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs
D04.210
Fused-Ring Compounds
D04.210.500.054.079.129.284
Loteprednol Etabonate
D04.210.500.054.079.129.891
Wortmannin