Homoharringtonine [homoharringtonin]
topical
1
- Terms
-
cefalotaxin
Ceflatonin
omacetaxin
omacetaxin mepesukcinát
Synribo
-
Ceflatonin
Cephalotaxine
Homoharringtonine (3(R))-isomer
Omacetaxine
Omacetaxine Mepesuccinate
Synribo
Persistent link
https://www.medvik.cz/link/D000077863
Definition
Semisynthetic derivative of harringtonine that acts as a protein synthesis inhibitor and induces APOPTOSIS in tumor cells. It is used in the treatment of MYELOID LEUKEMIA, CHRONIC.
- DUI
- D000077863 MeSH Browser
- CUI
- M0041919
- CAS
- Cephalotaxine, O3-((2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methyl-1-oxoheptyl)-
- History note
- 2019 (1972)
- Public note
- 2019; HOMOHARRINGTONINE was indexed under HARRINGTONINES 1978-2018; under ALKALOIDS and ANTINEOPLASTIC AGENTS 1972-1977; and under DIOXOLES 1972-1976
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AA
- analogs & derivatives
- AN
- analysis
- AI
- antagonists & inhibitors
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 1
- TO
- toxicity
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs
homoharringtonine, 3H-labeled, (3(R))-isomer Chemical MeSH Browser