Baclofen [baklofen]
- Terms
-
Baclofen
-
Apo-Baclofen
Atrofen
Ba-34,647
Ba-34647
Baclofen AWD
Baclofène-Irex
Baclophen
Baclospas
beta-(Aminomethyl)-4-chlorobenzenepropanoic Acid
beta-(p-Chlorophenyl)-gamma-aminobutyric Acid
Chlorophenyl GABA
CIBA-34,647-BA
Clofen
Gen-Baclofen
Genpharm
Lebic
Lioresal
Liorésal
Nu-Baclo
PCP-GABA
PMS-Baclofen
A GAMMA-AMINOBUTYRIC ACID derivative that is a specific agonist of GABA-B RECEPTORS. It is used in the treatment of MUSCLE SPASTICITY, especially that due to SPINAL CORD INJURIES. Its therapeutic effects result from actions at spinal and supraspinal sites, generally the reduction of excitatory transmission.
- DUI
- D001418 MeSH Browser
- CUI
- M0002117
- RN
- H789N3FKE8
- CAS
- Benzenepropanoic acid, beta-(aminomethyl)-4-chloro-
- Previous indexing
- Chlorobenzenes (1974); Aminobutyric Acids (1972-1974)
- History note
- 80(75); was see under AMINOBUTYRIC ACIDS 1975-79
- Public note
- 80; was see under AMINOBUTYRIC ACIDS 1975-79
Allowable subheadings
- AD
- administration & dosage 61
- AE
- adverse effects 17
- AG
- agonists 0
- AA
- analogs & derivatives 1
- AN
- analysis 0
- AI
- antagonists & inhibitors 1
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- EC
- economics 0
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 0
- PK
- pharmacokinetics 6
- PD
- pharmacology 33
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 60
- TO
- toxicity 0
- UR
- urine 0