A class of drugs producing both physiological and psychological effects through a variety of mechanisms. They can be divided into specific agents, e.g., affecting an identifiable molecular mechanism unique to target cells bearing receptors for that agent, and nonspecific agents, those producing effects on different target cells and acting by diverse molecular mechanisms. Those with nonspecific mechanisms are generally further classed according to whether they produce behavioral depression or stimulation. Those with specific mechanisms are classed by locus of action or specific therapeutic use. (From Gilman AG, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p252)

Annotation

general or unspecified; prefer specifics

obecné nebo nevymezené, dej přednost deskriptoru přesnější skupiny látek nebo druhu léčiv; zvaž také deskriptory CENTRÁLNÍ NERVOVÝ SYSTÉM s podheslem /účinky léků a MOZEK s podheslem /účinky léků

DUI

D002491 MeSH Browser

CUI

M0003803

History note

79; was NON MESH before 1979

Online note

consider also CENTRAL NERVOUS SYSTEM /DE & BRAIN /DE

Public note

79