A class of lipoproteins of small size (4-13 nm) and dense (greater than 1.063 g/ml) particles. HDL lipoproteins, synthesized in the liver without a lipid core, accumulate cholesterol esters from peripheral tissues and transport them to the liver for re-utilization or elimination from the body (the reverse cholesterol transport). Their major protein component is APOLIPOPROTEIN A-I. HDL also shuttle APOLIPOPROTEINS C and APOLIPOPROTEINS E to and from triglyceride-rich lipoproteins during their catabolism. HDL plasma level has been inversely correlated with the risk of cardiovascular diseases.

Annotation

hyperalphalipoproteinemia = LIPOPROTEINS, HDL /blood (IM) + HYPERLIPOPROTEINEMIAS (IM); hypoalphalipoproteinemia = LIPOPROTEINS, HDL /blood (IM) + HYPOLIPOPROTEINEMIAS (IM); familial hypoalphalipoproteinemia = TANGIER DISEASE; /defic: consider also HYPOLIPOPROTEINEMIAS

DUI

D008075 MeSH Browser

CUI

M0012584

Previous indexing

Lipoproteins (1966-1971)

History note

74(72)

Public note

74