Quinidine [chinidin]
- Terms
- 
            Adaquin 
 Apo-Quinidine
 Chinidin
 Quincardine
 Quinidex
 Quinidine Sulfate
 Quinora
An optical isomer of quinine, extracted from the bark of the CHINCHONA tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular ACTION POTENTIALS, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.
- DUI
- D011802 MeSH Browser
- CUI
- M0018341
- CAS
- Cinchonan-9-ol, 6'-methoxy-, (9S)-
Allowable subheadings
- AD
- administration & dosage 5
- AE
- adverse effects 13
- AG
- agonists
- AA
- analogs & derivatives 2
- AN
- analysis 2
- AI
- antagonists & inhibitors
- BL
- blood 3
- CF
- cerebrospinal fluid
- CS
- chemical synthesis 1
- CH
- chemistry 4
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 2
- PK
- pharmacokinetics 1
- PD
- pharmacology 14
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 18
- TO
- toxicity 4
- UR
- urine
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