Sp1 Transcription Factor [transkripční faktor Sp1]
topical
8
- Terms
-
Specificity Protein 1 Transcription Factor
Transcription Factor, Sp1
Persistent link
https://www.medvik.cz/link/D016329
Definition
Promoter-specific RNA polymerase II transcription factor that binds to the GC box, one of the upstream promoter elements, in mammalian cells. The binding of Sp1 is necessary for the initiation of transcription in the promoters of a variety of cellular and viral GENES.
- Annotation
- /drug eff /ultrastruct permitted; in titles & translations use SP1 (the figure one), not SPl (the letter l)
- DUI
- D016329 MeSH Browser
- CUI
- M0024957
- Previous indexing
- DNA-Binding Proteins (1986-1990); Transcription Factors (1986-1990)
- History note
- 2006(1991)
- Public note
- 2006; see TRANSCRIPTION FACTOR, SP1 1991-2005
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 0
- AG
- agonists 0
- AN
- analysis 0
- AI
- antagonists & inhibitors 1
- BI
- biosynthesis 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- DF
- deficiency 0
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 3
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 7
- PK
- pharmacokinetics 0
- PD
- pharmacology 0
- PH
- physiology 1
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 0
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs
D12.776.260.522.750.875
Sp4 Transcription Factor
D12.776.260.522.750.937
Sp7 Transcription Factor
D12.776.930.375.750.875
Sp4 Transcription Factor
D12.776.930.375.750.937
Sp7 Transcription Factor