Vaccines, DNA [DNA vakcíny]
- Terms
-
rekombinantní DNA vakcíny
vakcíny DNA
-
DNA Vaccine
DNA Vaccines
Naked DNA Vaccine
Naked DNA Vaccines
Recombinant DNA Vaccine
Recombinant DNA Vaccines
Vaccines, Recombinant DNA
Recombinant DNA vectors encoding antigens administered for the prevention or treatment of disease. The host cells take up the DNA, express the antigen, and present it to the immune system in a manner similar to that which would occur during natural infection. This induces humoral and cellular immune responses against the encoded antigens. The vector is called naked DNA because there is no need for complex formulations or delivery agents; the plasmid is injected in saline or other buffers.
- DUI
- D019444 MeSH Browser
- CUI
- M0028927
- Previous indexing
- Vaccines, Synthetic (1986-1996)
- History note
- 97
- Public note
- 97
Allowable subheadings
- AD
- administration & dosage 13
- AE
- adverse effects 4
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis 3
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 2
- CL
- classification 2
- EC
- economics
- GE
- genetics 10
- HI
- history
- IM
- immunology 26
- IP
- isolation & purification 2
- ME
- metabolism 1
- PK
- pharmacokinetics
- PD
- pharmacology 8
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 16
- TO
- toxicity
- UR
- urine
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