alpha-Tocopherol [alfa-tokoferol] topical
- Terms
-
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol
alpha-Tocopherol Acetate
alpha-Tocopherol Hemisuccinate
alpha-Tocopherol Succinate
alpha-Tocopheryl Calcium Succinate
d-alpha Tocopherol
d-alpha-Tocopheryl Acetate
R,R,R-alpha-Tocopherol
Tocopherol Acetate
Tocopherol Succinate
Tocopheryl Acetate
Vitamin E Succinate
A natural tocopherol and one of the most potent antioxidant tocopherols. It exhibits antioxidant activity by virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus. It has four methyl groups on the 6-chromanol nucleus. The natural d form of alpha-tocopherol is more active than its synthetic dl-alpha-tocopherol racemic mixture.
- Annotation
- deficiency: coordinate ALPHA-TOCOPHEROL with VITAMIN E DEFICIENCY
- DUI
- D024502
- CUI
- M0370590
- RN
- H4N855PNZ1
- Previous indexing
- Vitamin E (1965-2001)
- History note
- 2002; use VITAMIN E 1966-2001; for ALPHA-TOCOPHEROL SUCCINATE use VITAMIN E 1982-2007; for TOCOPHEROL ACETATE, D-ALPHA-TOCOPHEROL ACETATE, and TOCOPHEROL SUCCINATE use TOCOPHEROLS 2008-2013
- Public note
- 2002; see VITAMIN E 1966-2001; ALPHA-TOCOPHEROL SUCCINATE was indexed under VITAMIN E 1985-2008; ALPHA-TOCOPHEROL ACETATE was indexed under ALPHA-TOCOPHEROL 1980-2008, for TOCOPHEROL ACETATE, D-ALPHA-TOCOPHEROL ACETATE, and TOCOPHEROL SUCCINATE see TOCOPHEROLS 2008-2013
Allowable subheadings
- AD
- administration & dosage 11
- AE
- adverse effects 1
- AG
- agonists 0
- AA
- analogs & derivatives 4
- AN
- analysis 14
- AI
- antagonists & inhibitors 0
- BL
- blood 24
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 8
- CL
- classification 0
- EC
- economics 0
- HI
- history 0
- IM
- immunology 1
- IP
- isolation & purification 2
- ME
- metabolism 12
- PK
- pharmacokinetics 0
- PD
- pharmacology 16
- PO
- poisoning 0
- RE
- radiation effects 2
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 13
- TO
- toxicity 1
- UR
- urine 0
D03.383 Heterocyclic Compounds, 1-Ring
D03.383.663 Pyrans
D03.383.663.283 Benzopyrans
D03.383.663.283.909 Vitamin E
D03.383.663.283.909.750 Tocopherols
D03.383.663.283.909.750.249 alpha-Tocopherol
D03.383.663.283.909.750.374 beta-Tocopherol
D03.383.663.283.909.750.500 gamma-Tocopherol
D03.633 Heterocyclic Compounds, Fused-Ring
D03.633.100 Heterocyclic Compounds, 2-Ring
D03.633.100.150 Benzopyrans
D03.633.100.150.909 Vitamin E
D03.633.100.150.909.750 Tocopherols
D03.633.100.150.909.750.249 alpha-Tocopherol
D03.633.100.150.909.750.374 beta-Tocopherol
D03.633.100.150.909.750.500 gamma-Tocopherol