DNA Topoisomerase IV [DNA-topoisomerasa IV]
- Terms
-
DNA topoizomeráza IV
DNA topoizomeráza typu IV
DNA-topoizomeráza IV
protein parC
protein parE
topoizomeráza IV
topoizomeráza IV, podjednotka A
topoizomeráza IV, podjednotka B
-
parC Gene Product
parC Gene Product, Topo IV
parC Protein
parE Gene Product
parE Gene Product, Topo IV
parE Protein
Topo IV
Topoisomerase IV
Topoisomerase IV Subunit A
Topoisomerase IV Subunit B
A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Topoisomerase IV binds to DNA as a heterotetramer consisting 2 parC and 2 parE subunits. Topoisomerase IV is a decatenating enzyme that resolves interlinked daughter chromosomes following DNA replication.
- DUI
- D027101 MeSH Browser
- CUI
- M0181519
- Previous indexing
- DNA Topoisomerase (1990-1995); DNA Topoisomerase (ATP-Hydrolysing) (1991-2001)
- History note
- 2002; use DNA TOPOISOMERASE IV (NM) 1991-2001
- Public note
- 2002; DNA TOPOISOMERASE IV was indexed under TYPE II DNA TOPOISOMERASE 1991-2001
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- AI
- antagonists & inhibitors 1
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects 1
- EC
- economics
- GE
- genetics 2
- HI
- history
- IM
- immunology 1
- IP
- isolation & purification
- ME
- metabolism 1
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine