The first to be discovered member of the angiopoietin family. It may play a role in increasing the sprouting and branching of BLOOD VESSELS. Angiopoietin-1 specifically binds to and stimulates the TIE-2 RECEPTOR. Several isoforms of angiopoietin-1 occur due to ALTERNATIVE SPLICING of its mRNA.

Anotace

see SCR for organism-specific terms

DUI

D042683 MeSH Prohlížeč

CUI

M0270236

Předchozí užití

Angiogenesis Factor (2003); Membrane Glycoproteins (1997-2003)

Historická pozn.

2004; use ANGIOPOIETIN-1 (NM) 1997-2003

Veřejná pozn.

2004; ANGIOPOIETIN-1 was indexed under MEMBRANE GLYCOPROTEINS 1997-2003 & ANGIOGENESIS FACTOR 2003