14-alpha Demethylase Inhibitors [inhibitory 14-alfa-demethylasy]

topical
10
Terms

14-alfa-demethylasa - inhibitory
inhibitory 14-alfa-demetylázy
inhibitory CYP51

 

14alpha-Demethylase Inhibitors
CYP51 Inhibitors
Lanosterol 14 alpha-Demethylase Inhibitors

Persistent link   https://www.medvik.cz/link/D058888
Definition

Compounds that specifically inhibit STEROL 14-DEMETHYLASE. A variety of azole-derived ANTIFUNGAL AGENTS act through this mechanism.

DUI
D058888 MeSH Browser
CUI
M0545196
History note
2011
Public note
2011

Allowable subheadings

AD
administration & dosage 4
AE
adverse effects 3
AN
analysis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry 1
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics 4
PD
pharmacology 2
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use 7
TO
toxicity
UR
urine

D Chemicals and Drugs
D27 Chemical Actions and Uses 374
D27.505 Pharmacologic Actions 408
D27.505.389 Metabolic Side Effects of Drugs and Substances 48
D27.505.389.500 Cytochrome P-450 Enzyme Inhibitors 93
D27.505.389.500.059 14-alpha Demethylase Inhibitors 10
D27.505.389.500.120 Cytochrome P-450 CYP1A2 Inhibitors 7
D27.505.389.500.260 Cytochrome P-450 CYP2B6 Inhibitors
D27.505.389.500.308 Cytochrome P-450 CYP2C8 Inhibitors
D27.505.389.500.315 Cytochrome P-450 CYP2C9 Inhibitors 1
D27.505.389.500.319 Cytochrome P-450 CYP2C19 Inhibitors 2
D27.505.389.500.368 Cytochrome P-450 CYP2D6 Inhibitors 17
D27.505.389.500.421 Cytochrome P-450 CYP2E1 Inhibitors 4
D27.505.389.500.503 Cytochrome P-450 CYP3A Inhibitors 27
D27.505.519 Molecular Mechanisms of Pharmacological Action 89
D27.505.519.389 Enzyme Inhibitors 873
D27.505.519.389.335 Cytochrome P-450 Enzyme Inhibitors 93
D27.505.519.389.335.059 14-alpha Demethylase Inhibitors 10
D27.505.519.389.335.120 Cytochrome P-450 CYP1A2 Inhibitors 7
D27.505.519.389.335.260 Cytochrome P-450 CYP2B6 Inhibitors
D27.505.519.389.335.308 Cytochrome P-450 CYP2C8 Inhibitors
D27.505.519.389.335.319 Cytochrome P-450 CYP2C19 Inhibitors 2
D27.505.519.389.335.329 Cytochrome P-450 CYP2C9 Inhibitors 1
D27.505.519.389.335.368 Cytochrome P-450 CYP2D6 Inhibitors 17
D27.505.519.389.335.421 Cytochrome P-450 CYP2E1 Inhibitors 4
D27.505.519.389.335.503 Cytochrome P-450 CYP3A Inhibitors 27
D27.505.519.389.870 Steroid Synthesis Inhibitors 1
D27.505.519.389.870.100 14-alpha Demethylase Inhibitors 10
D27.505.519.389.870.200 5-alpha Reductase Inhibitors 75
D27.505.519.389.870.300 Aromatase Inhibitors 286
D27.505.696 Physiological Effects of Drugs 52
D27.505.696.399 Hormones, Hormone Substitutes, and Hormone Antagonists 43
D27.505.696.399.450 Hormone Antagonists 46
D27.505.696.399.450.855 Steroid Synthesis Inhibitors 1
D27.505.696.399.450.855.100 14-alpha Demethylase Inhibitors 10
D27.505.696.399.450.855.200 5-alpha Reductase Inhibitors 75
D27.505.696.399.450.855.300 Aromatase Inhibitors 286

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