Initially, molecular hydrogen was considered a physiologically inert and non-functional gas. However, experimental and clinical studies have shown that molecular hydrogen has anti-inflammatory, anti-apoptotic, and strong selective antioxidant effects. This study aimed to evaluate the effects of 60 minutes of molecular hydrogen inhalation on respiratory gas analysis parameters using a randomized, double-blind, placebo-controlled, crossover design. The study was conducted at Faculty of Physical Culture, Palacký University Olomouc from September 2022 to March 2023. Twenty, physically active female participants aged 22.1 ± 1.6 years who inhaled either molecular hydrogen or ambient air through a nasal cannula (300 mL/min) for 60 minutes while resting were included in this study. Metabolic response was measured using indirect calorimetry. Breath-by-breath data were averaged over four 15-minute intervals. Compared with placebo (ambient air), molecular hydrogen inhalation significantly decreased respiratory exchange ratio and ventilation across all intervals. Furthermore, the change in respiratory exchange ratio was negatively correlated with body fat percentage from 30 minutes onwards. In conclusion, 60 minutes of resting molecular hydrogen inhalation significantly increased resting fat oxidation, as evidenced by decreased respiratory exchange ratio, particularly in individuals with higher body fat percentages.
- MeSH
- Administration, Inhalation MeSH
- Adult MeSH
- Double-Blind Method MeSH
- Cross-Over Studies MeSH
- Humans MeSH
- Young Adult MeSH
- Rest * MeSH
- Placebos MeSH
- Hydrogen * administration & dosage pharmacology MeSH
- Healthy Volunteers MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Young Adult MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Randomized Controlled Trial MeSH
- MeSH
- Adaptation, Biological MeSH
- Exercise * physiology MeSH
- Energy Metabolism physiology MeSH
- Muscle Fibers, Skeletal physiology metabolism MeSH
- Humans MeSH
- Lipid Metabolism MeSH
- Carbohydrate Metabolism MeSH
- Oxidative Phosphorylation MeSH
- Physical Exertion physiology MeSH
- Physical Fitness physiology MeSH
- Check Tag
- Humans MeSH
- Publication type
- Review MeSH
Purpose: Molecular hydrogen has been shown to possess antioxidant, anti-inflammatory, ergogenic, and recovery-enhancing effects. This study aimed to assess the effect of molecular hydrogen administration on muscle performance, damage, and perception of soreness up to 24 h of recovery after two strenuous training sessions performed on the same day in elite fin swimmers. Methods: Eight females (mean ± SD; age 21.5 ± 5.0 years, maximal oxygen consumption 45.0 ± 2.5 mL.kg-1.min-1) and four males (age 18.9 ± 1.3 years, maximal oxygen consumption 52.2 ± 1.7 mL.kg-1.min-1) performed 12 × 50 m sprints in the morning session and a 400 m competitive performance in the afternoon session. Participants consumed hydrogen-rich water (HRW) or placebo 3 days before the sessions (1,260 mL/day) and 2,520 mL on the experimental day. Muscle performance (countermovement jump), muscle damage (creatine kinase), and muscle soreness (100 mm visual analogue scale) were measured during the experimental day and at 12 and 24 h after the afternoon session. Results: HRW compared to placebo reduced blood activity of creatine kinase (156 ± 63 vs. 190 ± 64 U.L-1, p = 0.043), muscle soreness perception (34 ± 12 vs. 42 ± 12 mm, p = 0.045), and improved countermovement jump height (30.7 ± 5.5 cm vs. 29.8 ± 5.8 cm, p = 0.014) at 12 h after the afternoon session. Conclusion: Four days of HRW supplementation is a promising hydration strategy for promoting muscle recovery after two strenuous training sessions performed on the same day in elite fin swimmers. Clinical Trial Registration: clinicaltrials.gov, identifier NCT05799911.
- Publication type
- Journal Article MeSH
Cíl: Primárním cílem studie bylo zjistit odezvu nitroočního tlaku (NOT) na rychlý příjem vody sycené vodíkem (HRW) ve srovnání s obyčejnou vodou (placebem) u zdravých osob. Dále byl sledován dopad příjmu HRW na centrální tloušťku rohovky (CCT). Subjekty a metodika: Do studie bylo zařazeno 24 zdravých dobrovolníků (5 mužů a 19 žen) ve věku od 20 do 33 let, u každého bylo měřeno vždy jen jedno oko. Jednalo se o prospektivní, randomizovanou, dvojitě zaslepenou studii s crossover designem. Každý proband podstoupil dvě části experimentu, náhodně rozdělené do dvou různých dnů. V každé z částí experimentu bylo každému účastníkovi během 15 minut podáno 1260 ml HRW nebo placeba ve třech dávkách. Před a po konzumaci vody byl všem účastníkům měřen NOT a CCT, a to po dobu 75 min od zahájení konzumace. Výsledky: HRW i placebo navodily signifikantní nárůst NOT. Maximální změna oproti výchozí hodnotě byla 2,7 mmHg ±2,0 mmHg v 25. minutě od zahájení experimentu při konzumaci HRW a 1,4 mmHg ±2,0 mmHg v 35. minutě u placeba. Statisticky signifikantní rozdíl mezi hodnotami NOT po vypití HRW a placeba nebyl zjištěn, avšak po vypití HRW se vyskytlo významně více klinicky významných individuálních odchylek (58 %) oproti placebu (25 %). V případě CCT nebyly během experimentu zjištěny žádné signifikantní změny. Závěr: Rychlý příjem 1260 ml HRW i obyčejné vody působí u zdravých jedinců statisticky významný nárůst NOT oproti výchozí hodnotě. V případě HRW byl tento nárůst u většiny subjektů významný i z klinického hlediska. Výsledky tak naznačují, že rychlý příjem HRW může z hlediska NOT představovat vyšší riziko než placebo. V případě rizikových skupin, jako jsou osoby s glaukomem, suspektním glaukomem nebo oční hypertenzí, je však nutné tento závěr ověřit dalšími studiemi.
Purposes: The primary aim of the study was to assess the response of intraocular pressure (IOP) to the acute ingestion of hydrogen-rich water (HRW) compared to hydrogen-free water (placebo) in healthy subjects. The effect of HRW intake on central corneal thickness (CCT) was also monitored. Subjects and Methods: Twenty-four healthy volunteers (5 men, 19 women) aged between 20 and 33 were included in the study, in which one eye of each subject was measured. The study was prospective, randomized and double-blind, with crossover design. Each subject underwent two parts of the experiment, each part on a different day and in random order. In each part of experiment, a total volume of 1260 ml of HRW or placebo was administered over 15 minutes in three doses. IOP and CCT were measured before and during the course of 75 minutes from the start of the HRW or placebo intake. Results: Administration of both HRW and the placebo caused a significant increase in IOP. The maximum IOP increase was 2.7 mmHg ±2.0 mmHg in minute 25 after the commencement of the experiment (HRW intake), and 1.4 mmHg ±2.0 mmHg in minute 35 (placebo intake). The values of IOP did not differ significantly between both parts, but there were significantly more clinically significant individual IOP increases after HRW intake (58%) compared to the placebo (25%). CCT did not change significantly during the experiment. Conclusion: The rapid intake of 1260 ml of both HRW and hydrogen-free water causes a statistically significant increase in IOP compared to the baseline in healthy individuals. In the case of HRW, the increase was also clinically significant in most of the subjects. Thus, the results indicate that acute intake of HRW may pose a higher risk than placebo intake in terms of IOP. However, in the case of risk groups such as subjects with glaucoma, ocular hypertension or suspected glaucoma, it is necessary to verify this conclusion by further studies.
Východiska Jednorázová vytrvalostní pohybová aktivita u netrénovaných osob je spojována s výskytem opožděné svalové bolesti související s probíhajícím lokální zánětem a zvýšeným oxidativním stresem. Molekulární vodík (H2) je nový selektivně působící antioxidant a protizánětlivě působící látka. Cíl Hlavním cílem studie bylo posoudit vliv aplikace H2 obohacené vody (HRW) na rozvoj pozátěžové svalové bolesti během 24 hod od ukončení 5 km běhu. Metodika V rámci randomizované studie podstoupilo 12 vytrvalostně netrénovaných mužů ve věku 23,6 ± 3,4 roku běh na 5 km s cílem dosažení nejlepšího běžeckého výkonu. V průběhu dvou dnů před zatížením a do 60 min po ukončení byla probandům aplikována celková dávka 3780 ml HRW nebo placeba. V časech 0 h, 1 h, 4 h a 24 h po zátěži byla hodnocena bolestivost dolních končetin pomocí 100 mm vizuální analogové škály. Odstup mezi oběma měřeními činil 7 dnů. Výsledky Aplikace HRW v porovnání s placebem signifikantně redukuje pozátěžovou bolest dolních končetin během 1. h (41 ± 21 vs. 27 ± 13 mm; p=0,017) a 4. h (34 ± 21 vs. 22 ± 15 mm; p=0,029). Rozdíly po 24 h se blížily statistické významnosti (36 ± 27 vs. 26 ± 16 mm; p = 0,081). Závěr Konzumace HRW významně snižuje pozátěžovou percepci svalové bolesti s tendencí zmírňovat i opožděnou svalovou bolest po absolvování 5km běhu u netrénované populace.
OBJECTIVES: In 2020, measures against the spread of COVID-19 were adopted, including nationwide school closures, restrictions on the free movement of persons and leisure time sports activities. The aim was to assess the impact of COVID-19-associated restrictions on the performance of paediatric and adolescent competitive athletes by comparing basic anthropometric and performance parameters. METHODS: The sample comprised 389 participants (115 girls, 274 boys). All participants were examined during regular preventive sports health checks from September to November 2019 and a year later. At the initial examination, the mean age of the entire sample was 12.2 ± 2.7 years (median 12.0, minimum 7.0; maximum 17.0). The examination consisted of a complete medical history and physical examination including maximal exercise testing on a leg cycle ergometer. RESULTS: In the entire sample, as well as in the boy and girl subgroups, body height, weight, body mass index (BMI), BMI percentile, and power output significantly increased according to a percentile graph for boys and girls in 2020. A reduction in power output (W/kg) was found. By 2020, W/kg dropped in 56.4% of the youngest participants (7-13 years), 75% of those aged 14-16 years and 64.9% of the oldest individuals (16-17 years). The percentage of the youngest children with power output reductions was statistically significantly lower than the percentages of the other age subgroups (p = 0.007). There were no significant differences in results between genders. CONCLUSIONS: Performance and anthropometric parameters worsened especially among older children. This should be reflected when planning epidemic measures in case of any similar situation in the future.
- MeSH
- Anthropometry methods MeSH
- COVID-19 * epidemiology MeSH
- Child MeSH
- Body Mass Index MeSH
- Humans MeSH
- Adolescent MeSH
- Pandemics * MeSH
- Athletes MeSH
- Check Tag
- Child MeSH
- Humans MeSH
- Adolescent MeSH
- Male MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Geographicals
- Czech Republic MeSH
Background: In ice hockey, regular off-ice testing can serve as a controlling mechanism for a training program's effectiveness. Objective: The main aim of this study was to describe changes in selected morphological and physiological parameters, intended to be relevant for a complex ice hockey performance, after two months of pre-season training preparation following one month of an off-season period. Methods: The sample consisted of 22 adult male players aged 18-39 years from a top Czech ice hockey league team. Two laboratory testing procedures performed at the end of the off-season and after two months of the pre-season conditioning consisted of basic anthropometry and body composition measurements, countermovement jump (CMJ), and maximal incremental test focused on the assessment of various parameters, including maximal oxygen consumption (V̇O2max), maximal power output during the test (Pmax) or estimation of anaerobic threshold intensity (ANT). Results: After the pre-season, we found a significant decrease in body fat (13.7 vs. 11.4%, p < .001) and an increase in fat-free mass (74.2 vs. 76.6 kg, p < .001), V̇O2max (relative 48.8 vs. 52.6 ml.kg-1.min-1 p = .001; absolute 4.20 vs. 4.54 L.min-1, p < .001), Pmax (5.26 vs. 5.44 W.kg-1, p = .011), power output at ANT (4.07 vs. 4.35 W.kg-1, p < .001), and CMJ (44.9 vs. 47.1 cm, p = .002). Conclusions: Based on our results, two months of the pre-season training program led to a significant improvement in body composition and physical performance levels in professional Czech ice hockey players.
- MeSH
- Adult MeSH
- Hockey * MeSH
- Physical Conditioning, Human * methods MeSH
- Humans MeSH
- Athletic Performance MeSH
- Muscle Strength MeSH
- Physical Fitness MeSH
- Endurance Training methods MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Male MeSH
- Publication type
- Clinical Study MeSH
- Geographicals
- Czech Republic MeSH
PURPOSE: This study investigated the effects of acute, pre-exercise, hydrogen rich water (HRW) ingestion on running time to exhaustion at maximal aerobic speed in trained track and field runners. METHODS: Twenty-four, male runners aged 17.5 ± 1.8 years, with body mass index = 21.0 ± 1.3 kg⋅m-2, and maximal oxygen uptake = 55.0 ± 4.6 ml⋅kg-1⋅min-1 (mean ± standard deviation) participated in this randomized, double-blind, placebo-controlled crossover study. All runners ingested 1260 ml of HRW which was divided into four doses and taken at 120 min (420 ml), 60 min (420 ml), 30 min (210 ml), and 10 min (210 ml) prior to exercise. The running protocol consisted of three phases: warm-up performed at 10 km⋅h-1 for 3 min, followed by a transition phase performed at an individually determined speed (10 km⋅h-1 + maximal aerobic speed)/2 for 1 min, and finally the third phase performed at individual maximal aerobic speed until exhaustion. Time to exhaustion, cardiorespiratory variables, and post-exercise blood lactate concentration were measured. RESULTS: When running to exhaustion at maximal aerobic speed, compared with placebo, HRW had no significant effects on the following variables: time to exhaustion (217 ± 49 and 227 ± 53 s, p = 0.20), post-exercise blood lactate concentration (9.9 ± 2.2 and 10.1 ± 2.0 mmol⋅L-1, p = 0.42), maximal heart rate (186 ± 9 and 186 ± 9 beats⋅min-1, p = 0.80), and oxygen uptake (53.1 ± 4.5 and 52.2 ± 4.7 ml⋅kg-1⋅min-1, p = 0.33). No variable assessed as a candidate moderator was significantly correlated with time to exhaustion (Spearman's correlation coefficients ranged from -0.28 to 0.30, all p ≥ 0.16). CONCLUSIONS: Pre-exercise administration of 1260 ml of HRW showed no ergogenic effect on running performance to exhaustion at maximal aerobic speed in trained track and field runners.
- MeSH
- Double-Blind Method MeSH
- Physical Endurance * MeSH
- Cross-Over Studies MeSH
- Lactic Acid MeSH
- Oxygen pharmacology MeSH
- Track and Field * MeSH
- Humans MeSH
- Drinking MeSH
- Oxygen Consumption MeSH
- Hydrogen pharmacology MeSH
- Check Tag
- Humans MeSH
- Male MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Randomized Controlled Trial MeSH
BACKGROUND: Vibroacoustic therapy (VAT) uses low-frequency sound, often combined with listening to music, for therapeutic purposes. However, the impact of low-frequency vibration (LFV) on physiological functions and subjective perception is relatively unknown. METHODS: We conducted a randomized cross-over study with the aim of comparing the effect of constant LFV of 40 Hz, its amplitude modulation, and the placebo condition on heart rate variability (HRV), stress perception (measured by visual analogue scales for stress) and mood (measured by UWIST Mood Adjective Check List). RESULTS: Research experiments with various interventions (constant LFV with sound of nature (river in forest), amplitude modulation of the same LFV with sounds of nature and sounds of nature without LFV) were realised involving 24 participants. It was found there was an effect on HRV, stress perception and mood after the interventions. However, there were only seldomly experienced, and mostly nonsignificant, differences between the intervention conditions, so the effects may be attributed to factors other than LFV. CONCLUSIONS: Large scale experimental studies are needed to verify the preliminary findings and to explore various coinciding factors that may have influenced the results of this study, e.g., type of autonomic nervous system. We propose that the effect of LFV exposure may differ when combined with listening to music, and this hypothesis should be investigated in future studies.
- Publication type
- Journal Article MeSH
