BMI deviation
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OBJECTIVES: This study aimed to determine whether there is a relationship between common FTO (rs17817449) and MC4R (rs17782313) gene variants and body mass reduction or weight loss after a one-month lifestyle intervention in overweight/obese children. DESIGN AND METHODS: We genotyped 357 unrelated non-diabetic Czech children (age 13.7 ± 4.9 years, average BMI at baseline 30.8 ± 4.6 kg/m(2)). Biochemical and anthropometrical measurements were performed before and after 4 weeks of lifestyle interventions (comprising a reduction in energy intake to the age-matched optimum and a supervised exercise program consisting of 5 exercise units per day, 50 min each). RESULTS: The mean weight loss achieved was 6.2 ± 2.1 kg (P<0.001). Significant associations were found between a BMI decrease and the FTO and MC4R variants. Carriers of the FTO GG genotype and/or MC4R CC genotype lost significantly more body weight compared to noncarriers (P<0.0009 for BMI and P<0.002 for body weight). These differences remained significant following adjustment for sex, age and baseline values (P=0.004 for BMI and P=0.01 for body weight). CONCLUSIONS: FTO and MC4R gene variants modify the impact of an intensive lifestyle intervention on BMI decrease in overweight/obese children. Carriers of the FTO GG genotype and MC4R CC genotype benefit significantly more from the lifestyle intervention.
- MeSH
- dítě MeSH
- energetický příjem MeSH
- frekvence genu MeSH
- genetická epistáze MeSH
- genetické asociační studie MeSH
- index tělesné hmotnosti MeSH
- lidé MeSH
- mladiství MeSH
- nadváha genetika terapie MeSH
- obezita genetika terapie MeSH
- polymorfismus genetický MeSH
- programy na snížení hmotnosti MeSH
- proteiny genetika MeSH
- receptor melanokortinový typ 4 genetika MeSH
- redukční dieta MeSH
- sekvenční analýza DNA MeSH
- terapie cvičením MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
This cross sectional study focused on how Postural Stability (PS) indicators: body sway deviation (BSD) and body sway velocity (BSV), change with age and their association with levels of social and physical activity. Observational study: 80 older adults (aged: 60-96) were purposefully recruited from two sources: the University of the Third Age (TAU) (n = 35) and a residential care home (CH) (n = 45). Differences in the indicators of PS, approximated through Centre of Pressure (COP) measurements, were assessed by the Romberg Stance Test (Test A) subsequently repeated on 10 cm foam surface (Test B), using a Kistler Dynamometric Platform. The RCH Group was older, had higher BMI and was less socially and physically active, showed more body sway in all indicators compared to TAU group. For all participants body sway velocity (BSV) was significantly correlated with age. The strength of correlation of body sway deviation (BSD) with age was also significant but not as strong. The findings indicate in line with previous studies that deterioration in BSV is associated with poor PS more than deterioration in BSD.
- MeSH
- kinestezie fyziologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- pohybová aktivita MeSH
- posturální rovnováha fyziologie MeSH
- průřezové studie MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- sociální chování MeSH
- věkové faktory MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
Úvod a metódy: Cieľom štúdie bolo zhodnotiť vzťah medzi obezitou a závažnosťou hypertenzie u detí a adolescentov. Do štúdie bolo zaradených 109 pacientov s primárnou obezitou vo veku 7–18 rokov (14,1 ± 3,1). Pacienti boli rozdelení do 3 skupín podľa stupňa obezity na základe smerodajnej odchýlky body mass indexu (SDS BMI): Skupina 1 (n = 27): BMI SDS >1,65 a <3,28; Skupina 2 (n = 55): BMI SDS >3,29 a <4,91; Skupina3 (n = 27): BMI SDS >4,92. Definícia a hodnotenie stupňa hypertenzie bolo založené na posúdení percentilu priemernej hodnoty krvného tlaku v porovnaní s normami pre detský vek a nálože krvného tlaku (BP load), ktoré boli získané z 24-hodinového monitorovania krvného tlaku (ABPM). Výsledky: Normálny krvný tlak sa zistil iba u 24 % detí, 25 % malo prehypertenziu, 3 % hypertenziu a 48 % závažnú hypertenziu (BP load viac ako 50 %). Závažnosť hypertenzie stúpa signifikantne so stupňom obezity (p = 0,0027). Denný systolický (SDS = 0,32; 1,24; 1,86), diastolický (SDS = -0,42; 0,56; 0,93) a stredný arteriálny (SDS = -0,01; 0,85; 1,36) tlak stúpa signifikantne s BMI, kým nočný tlak ostáva elevovaný nezávisle od stupňa obezity. Izolovaná nočná hypertenzia bola pozorovaná u 25 % pacientov a chýbanie nočného poklesu krvného tlaku u 38 % pacientov. Záver: Takmer 50 % detí s obezitou a hypertenziou zistenou pri ABPM trpí závažnou hypertenziou. Hodnota BMI priamo súvisí so závažnosťou hypertenzie u detí a vzostupom krvného tlaku počas dňa.
Introduction and methods: The goal of our study was to analyze the association between obesity and the severity of ambulatory hypertension in obese children. A total of 109 patients with primary obesity ages 7 to 18 years (mean ± SD age 14.1 ± 3.1) were enrolled. Patients were divided into three groups according to body mass index (BMI) Z-scores: group 1 (n=27): BMI >1.65 and <3.28 standard deviation scores (SDS); group 2 (n=55): BMI >3.29 and < 4.91 SDS; group 3 (n=27): BMI >4.92 SDS. Definition and staging of ambulatory hypertension was based on blood pressure (BP) levels and BP load, obtained from ambulatory BP monitoring (ABPM). Results: Only 24% of individuals had ambulatory normotension, 25% had ambulatory prehypertension, 3% had hypertension, and 48% had severe ambulatory hypertension (BP load over 50%). The severity of hypertension increased significantly with the degree of obesity (P=0.0027). Daytime systolic (SDS=0.32, 1.24, 1.86), diastolic (SDS= -0.42, 0.56, 0.93), and mean arterial (SDS= -0.01, 0.85, 1.36) BPs increased significantly with increased BMI, whereas the nighttime pressure remained elevated regardless of the degree of obesity. Isolated nighttime hypertension was observed in 25% of patients and 38% were classified as nondippers. Conclusion: Almost 50% of children with obesity and hypertension detected on ABPM suffer from severe ambulatory hypertension. BMI is associated with the severity of ambulatory hypertension and the increase of daytime BP.
- MeSH
- časové faktory MeSH
- diastola MeSH
- dítě MeSH
- hypertenze * etiologie MeSH
- index tělesné hmotnosti * MeSH
- krevní tlak * fyziologie MeSH
- lidé MeSH
- měření krevního tlaku MeSH
- mladiství MeSH
- obezita * patofyziologie MeSH
- statistika jako téma MeSH
- systola MeSH
- výběr pacientů MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- práce podpořená grantem MeSH
We analyse the link between diet diversity, (which is a proxy of diet quality) and health outcomes measured by body-mass index (BMI) in a representative sample of Kosovar adults using household expenditure micro-data. Building on a household model of health production we devise a two-stage empirical strategy to estimate the determinants of diet diversity and its effect on BMI. Economic factors and demographic characteristics play an important role in the choice of balanced diets. Results from the BMI analysis support the hypothesis that diet diversity is associated with optimal BMI. One standard deviation increase in diet diversity leads to 2.3% increase in BMI of the underweight individuals and to 1.5% reduction in BMI of the obese individuals. The findings have important implications for food security policies aiming at enhancing the public health in Kosovo.
- MeSH
- dieta * MeSH
- dospělí MeSH
- ekonometrické modely MeSH
- hubenost epidemiologie MeSH
- index tělesné hmotnosti * MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- obezita epidemiologie MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- socioekonomické faktory * MeSH
- zdravotní stav MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Kosovo epidemiologie MeSH
Cíl: Hlavním cílem pilotní studie (podklad plánované celonárodní studie) bylo provést kvantitativní i kvalitativní monitoring výživových zvyklostí adolescentů. Dílčím cílem bylo srovnat vybrané parametry s rozsáhlou evropskou studií HELENA a defi novat, zda výběr stravy studentů nelékařských studijních oborů je ovlivněn odbornými znalostmi o zásadách zdravé výživy a liší se tak od laické adolescentní populace České republiky. Metody: Sběr kvantitativních dat byl realizován pomocí autorského dotazníku (35 položek), soubor celkem 131 respondentů (studenti nelékařských studijních oborů: Všeobecná sestra, Nutriční terapeut, Optometrie). Věkový průměr 24,0 let, směrodatná odchylka 3,75). Data byla vyhodnocena pomocí popisné (deskriptivní) statistiky s využitím absolutních a relativních četností. Výsledky: Z výsledků pilotní studie (realizované 12/2008–01/2009) vyplynulo, že respondenti přijímají nedostatečné množství ovoce a zeleniny. Více než 1 porci ovoce denně konzumuje 29,01 % respondentů a více než 1 porci zeleniny denně konzumuje 24,43 % respondentů. Naopak nadbytečný je příjem tzv. nevhodných potravin – snacků cukrovinky, tučná a sladká jídla, hranolky či nadměrně slazené nápoje). Na dotaz o množství přijímaných nevhodných potravin uvedlo 9,92 % respondentů příjem více než 1× denně a konzumaci 1× denně uvedlo 32,06 % respondentů (BMI v mezích normy, tj. ženy 19–23,9 a muži 20–24,9, dosáhlo 75 % respondentů, 10 % respondentů mělo pod normu sníženou hodnotu BMI a 15 % respondentů nad normu zvýšenou hodnotu BMI). Závěry: Chování respondentů pilotní studie a evropské mládeže se ve všech sledovaných oblastech (příjem ovoce, zeleniny, „nevhodných potravin“) shoduje.
Aims: The main goal of pilot study (background prospective nationwide study) was realize quantitative as well as quantitative monitoring of the nutrition customs by adult population. As partial goals has been established two goals: to compare selected parameters with long – range Th e European study HELENA and to defi ne if the food selection by paramedical students is infl uenced according to professional pieces of knowledge about principles healthy nutrition and its diff erent toward to laic adolescent population at Czech Republic. Methods: Th e quantitative data collection was realized by method of an authors questionnaire (35 items), set of 131 respondents (paramedical students: Nurse, Nutritionists, Optometrists). Average age was 24.0 years, standard deviation was 3.75. Data has been evaluated thanks to descriptive statistics with utilization absolute and relative rates. Results: Th e pilot study outcomes (realized 12/2008–01/2009) refer to fact that respondents are receiving a lack amount of fruit and vegetables. Daily consume more than one fruit portion 29,01 % of the respondents and daily consume more than one vegetable portion 24,43 % of the respondents. At the other side the amount of the “unfi tting” food – snacks (sweets, fatty food, chips or ickie drinks). On the question about amount of receiving unfi tting food indicated 9,92 % of respondents intake more than one portion and consummation of amount one portion per day indicated 32,06 % of the respondents (BMI in normal rates, i.e. women 19–23.9 and men 20–24.9 has got 75 % respondents, 10 % respondents has got decreased rate of BMI and 15 % respondents has got over normal increased rate of BMI). Conclusions: By the total outcomes comparison has found out that behave in the district of Czech and European adolescent population is consensual in all monitored attributes (intake of fruit, vegetable, “unfi tting food”).
- Klíčová slova
- adolescence, studie HELENA, fenomén adolescenční moratorium,
- MeSH
- fyziologie výživy mladistvých MeSH
- hodnocení stavu výživy MeSH
- index tělesné hmotnosti MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- nutriční stav MeSH
- pilotní projekty MeSH
- podvýživa MeSH
- průřezové studie MeSH
- průzkumy a dotazníky MeSH
- stravovací zvyklosti MeSH
- zdraví MeSH
- Check Tag
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
BACKGROUND: Assessing the relationship between lung cancer and metabolic conditions is challenging because of the confounding effect of tobacco. Mendelian randomization (MR), or the use of genetic instrumental variables to assess causality, may help to identify the metabolic drivers of lung cancer. METHODS AND FINDINGS: We identified genetic instruments for potential metabolic risk factors and evaluated these in relation to risk using 29,266 lung cancer cases (including 11,273 adenocarcinomas, 7,426 squamous cell and 2,664 small cell cases) and 56,450 controls. The MR risk analysis suggested a causal effect of body mass index (BMI) on lung cancer risk for two of the three major histological subtypes, with evidence of a risk increase for squamous cell carcinoma (odds ratio (OR) [95% confidence interval (CI)] = 1.20 [1.01-1.43] and for small cell lung cancer (OR [95%CI] = 1.52 [1.15-2.00]) for each standard deviation (SD) increase in BMI [4.6 kg/m2]), but not for adenocarcinoma (OR [95%CI] = 0.93 [0.79-1.08]) (Pheterogeneity = 4.3x10-3). Additional analysis using a genetic instrument for BMI showed that each SD increase in BMI increased cigarette consumption by 1.27 cigarettes per day (P = 2.1x10-3), providing novel evidence that a genetic susceptibility to obesity influences smoking patterns. There was also evidence that low-density lipoprotein cholesterol was inversely associated with lung cancer overall risk (OR [95%CI] = 0.90 [0.84-0.97] per SD of 38 mg/dl), while fasting insulin was positively associated (OR [95%CI] = 1.63 [1.25-2.13] per SD of 44.4 pmol/l). Sensitivity analyses including a weighted-median approach and MR-Egger test did not detect other pleiotropic effects biasing the main results. CONCLUSIONS: Our results are consistent with a causal role of fasting insulin and low-density lipoprotein cholesterol in lung cancer etiology, as well as for BMI in squamous cell and small cell carcinoma. The latter relation may be mediated by a previously unrecognized effect of obesity on smoking behavior.
- MeSH
- fenotyp MeSH
- index tělesné hmotnosti MeSH
- inzulin krev MeSH
- inzulinová rezistence MeSH
- jednonukleotidový polymorfismus MeSH
- lidé MeSH
- lipidy krev MeSH
- mendelovská randomizace * MeSH
- nádory plic krev komplikace metabolismus patologie MeSH
- obezita krev komplikace MeSH
- omezení příjmu potravy MeSH
- pravděpodobnostní funkce MeSH
- rizikové faktory MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
The study aimed to examine associations of neighborhood built environments and proximity of food outlets (BE measures) with body weight status using pooled data from an international study (IPEN Adult). Objective BE measures were calculated using geographic information systems for 10,008 participants (4463 male, 45%) aged 16-66 years in 14 cities. Participants self-reported proximity to three types of food outlets. Outcomes were body mass index (BMI) and overweight/obesity status. Male and female weight status associations with BE measures were estimated by generalized additive mixed models. Proportion (95% CI) of overweight (BMI 25 to <30) ranged from 16.6% (13.1, 19.8) to 41.1% (37.3, 44.7), and obesity (BMI ≥ 30) from 2.9% (1.3, 4.4) to 31.3% (27.7, 34.7), with Hong Kong being the lowest and Cuernavaca, Mexico highest for both proportions. Results differed by sex. Greater street intersection density, public transport density and perceived proximity to restaurants (males) were associated with lower odds of overweight/obesity (BMI ≥ 25). Proximity to public transport stops (females) was associated with higher odds of overweight/obesity. Composite BE measures were more strongly related to BMI and overweight/obesity status than single variables among men but not women. One standard deviation improvement in the composite measures of BE was associated with small reductions of 0.1-0.5% in BMI but meaningful reductions of 2.5-5.3% in the odds of overweight/obesity. Effects were linear and generalizable across cities. Neighborhoods designed to support public transport, with food outlets within walking distance, may contribute to global obesity control.
- MeSH
- charakteristiky bydlení MeSH
- doprava statistika a číselné údaje MeSH
- dospělí MeSH
- geografické informační systémy statistika a číselné údaje MeSH
- index tělesné hmotnosti * MeSH
- internacionalita * MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- obezita * MeSH
- potraviny * MeSH
- průřezové studie MeSH
- restaurace * MeSH
- sexuální faktory MeSH
- velkoměsta MeSH
- vytvořené prostředí * MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Research Support, N.I.H., Extramural MeSH
- Geografické názvy
- velkoměsta MeSH
The prevalence of childhood overweight is a major social and public health issue, and primary assessment should focus on early and middle childhood, because weight gain in these phases constitutes a strong predictor of subsequent negative outcomes. Studies on community samples have shown that growth curves may follow linear or non-linear trajectories from early to middle childhood, and can differ based on sex. Overweight children may exhibit a combination of physiological and psychosocial issues, and several studies have demonstrated an association between overweight and internalizing/externalizing behavior. Nevertheless, there is a dearth of longitudinal studies on depressive and aggressive symptoms in children with high BMI. This study adopted a growth curve modeling over three phases to: (1) describe BMI trajectories in two groups of children aged 2-8 (overweight and normal weight) from a community sample; (2) describe the developmental trajectories of children's aggressive and depressive symptoms from 2 to 8 years of age. Results indicate higher BMI in 2-year-old girls, with males catching up with them by age 8. While overweight females' BMIs were consistently high, males' increased at 5 and 8 years. The mean scores for aggressive symptoms at T1 (2 years of age) were the same in all subjects, but a significant deviation occurred from T1 to T2 in both samples, in divergent directions. With regards to children's depressive symptoms, the two groups had different starting points, with normal weight children scoring lower than overweight youths. Overweight females showed lower depressive scores than overweight males at T1, but they surpassed boys before T2, and showed more maladaptive symptoms at T3. This study solicits professionals working in pediatric settings to consider overweight children's psychopathological risk, and to be aware that even when children's BMI does not increase from 2 to 8 years, their psychopathological symptoms may grow in intensity.
- MeSH
- agrese * MeSH
- biologické modely MeSH
- deprese * MeSH
- dítě MeSH
- index tělesné hmotnosti MeSH
- lidé MeSH
- longitudinální studie MeSH
- obezita dětí a dospívajících patofyziologie psychologie MeSH
- předškolní dítě MeSH
- sexuální faktory MeSH
- vývoj dítěte MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- mužské pohlaví MeSH
- předškolní dítě MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
BACKGROUND: Bioelectric impedance analysis (BIA) is commonly used in research to assess body composition. However, studies that validate the accuracy of BIA exclusively in post-menopausal women are lacking. The main purpose of the present study was to evaluate the agreement of multi-frequency (MF)-BIA and single-frequency (SF)-BIA with dual-energy X-ray absorptiometry (DXA) in the estimation of fat mass (FM) and fat-free mass (FFM) among post-menopausal women with variation in body mass index (BMI) and physical activity (PA). METHODS: FM and FFM were estimated by BIA and DXA in 146 post-menopausal women with a mean (SD) age of 62.8 (5.2) years. PA was determined by an accelerometer. RESULTS: The mean (SD) difference between MF-BIA and DXA was -1.8 (1.8) kg (P = 0.08) and 1.3 (1.8) kg (P = 0.01) for FM and FFM, respectively. SF-BIA provided a significantly lower estimate of FM [-2.0 (2.2) kg; P = 0.04] and a higher estimate of FFM [1.8 (2.4) kg; P < 0.01] compared to DXA. MF-BIA provided significantly better estimates of FM and FFM with narrower limits of agreement than SF-BIA in obese and insufficiently active subjects. In other BMI and PA groups, both BIA devices showed a similar deviation from DXA. CONCLUSIONS: BIA tends to underestimate FM and overestimate FFM relative to DXA. MF-BIA appears to be a more appropriate method for the assessment of body composition than SF-BIA in post-menopausal woman with BMI >30 kg/m(2) and in those who are insufficiently active.
- MeSH
- absorpční fotometrie * MeSH
- akcelerometrie MeSH
- cvičení fyziologie MeSH
- elektrická impedance * MeSH
- index tělesné hmotnosti * MeSH
- lidé středního věku MeSH
- lidé MeSH
- obezita patofyziologie MeSH
- postmenopauza fyziologie MeSH
- sedavý životní styl MeSH
- senioři MeSH
- složení těla * MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- srovnávací studie MeSH
PURPOSE: The aim of study was to compare growth, nutritional status and incidence of chest wall deformities and scoliosis in survivors of large congenital diaphragmatic hernia (CDH) defect (Gore-Tex patch reconstruction) with survivors with smaller defects and primary reconstruction. MATERIALS AND METHODS: An anthropometric study of 53 children who underwent CDH repair in neonatal period was carried out. Weight, height, and skin-fold thickness were measured, scoliosis and chest wall deformity were evaluated. Body mass index (BMI) and thoracic index (TI) were calculated using standard rules. The measured data were compared with national population standard with the use of standard deviation score (SDS). According to the type of diaphragmatic reconstruction, the patients were divided into two groups [Gore-Tex patch (10) versus primary repair (43)]. Student t test and Fisher exact tests were used for statistical analysis. RESULTS: Pectus excavatum was found in 25 (47%) patients, poor posture in 33% and significant scoliosis in 5%. Compared with the population norm, CDH children had a significantly lower body height SDS (mean -0.39, p < 0.05), weight SDS (mean -0.75, p < 0.001), BMI (mean SDS -0.68, p < 0.001) and lower TI (mean SDS -0.62, p < 0.01). Gore-Tex versus primary repair group significantly differed in incidence of pectus excavatum and BMI (PE: p = 0.027, BMI SDS: p = 0.016). A majority of anthropometric parameters (weight, height, thoracic index, and thorax circumference) and incidence of scoliosis and poor posture in children after Gore-Tex patch reconstruction did not significantly differ from children after primary repair. CONCLUSION: The differences in some anthropometric parameters (weight, BMI, and TI) and in the skeletal deformity suggest that the CDH not only disturbs normal lung growth, but also seems to have implications on some other aspects of somatic development. Whether these changes could be related to the type of diaphragmatic reconstruction or rather to the size of the defect remains uncertain.
- MeSH
- biokompatibilní materiály MeSH
- brániční hernie komplikace diagnóza chirurgie MeSH
- chirurgické síťky MeSH
- dítě MeSH
- hrudník vpáčený epidemiologie etiologie prevence a kontrola MeSH
- incidence MeSH
- index tělesné hmotnosti MeSH
- lidé MeSH
- polytetrafluoroethylen MeSH
- prognóza MeSH
- rentgendiagnostika hrudníku MeSH
- retrospektivní studie MeSH
- skolióza epidemiologie etiologie prevence a kontrola MeSH
- vrozená brániční kýla MeSH
- zákroky plastické chirurgie metody MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- srovnávací studie MeSH
- Geografické názvy
- Česká republika MeSH