Introduction: Vitamin D has several functions in the body. It affects calcium metabolism and various physiological functions, such as immunity, CNS, pregnancy, the cardiovascular system, etc. Its intake is mainly mediated by synthesis in the skin from 7-dehydrocholesterol thanks to UV radiation – specifically UVB with a wavelength of 290–320 nm. Another source of this vitamin is food. This article deals with vitamin D intake from food. Goal: This paper aims to map the connection between the amount of vitamin D from an adult diet and its level in the blood. Methods: To determine the level of vitamin D in the blood, we used the daily records of individual respondents according to the amount and type of food consumed for 9 months. During the research, venous blood was taken twice from the respondents to examine calcidiol, calcium, phosphatemia, and alkaline phosphatase levels. The study involved 9 respondents (6 women and 3 men) between 19–28 years, whose diets were monitored for 9 months. Results: The diet’s daily intake of vitamin D corresponded to literature data, i.e., 3.55 μg. Higher intake was found on weekends and lower in the autumn months. A correlation was found between vitamin D and calcium levels. No correlation was found between vitamin D levels and alkaline phosphatase and phosphatemia. Conclusion: The results show that the intake of vitamin D from food in Czech conditions is sufficient.

The relationship between glycaemia and lipoprotein metabolism has not been completely clarified, and slight differences may be found between local authors, trials and evaluated parameters. Therefore this cross-sectional study investigated fasting cholesterol and glucose levels along with the determination of atherogenic index in a cohort of healthy individuals from the Czech Republic in relation to their fasting C-peptide levels. Data were collected between 2009 and 2018 and a total of 3189 individuals were stratified by C-peptide reference range (260-1730 pmol/l) into three groups - below (n = 111), within (n = 2952) and above (n = 126). Total, HDL, LDL cholesterol and atherogenic index were used to compare lipoprotein levels by relevant C-peptide concentrations. Participants using the supplements to affect lipid or glycaemia metabolism were excluded from this study. The evaluation of blood parameters in a fasting state included correlations between C-peptide and cholesterols, differences of variances (F-test) and the comparison of lipoprotein mean values (t-test) between the groups created by the C-peptide reference range. Mean values of total (4.9, 5.1, 5.3 mmol/l), LDL (2.6, 3.1, 3.4 mmol/l) cholesterol and atherogenic index (2.1, 2.8, 3.7) were higher with increasing C-peptide levels, whereas HDL was inversely associated with fasting C-peptide concentration. A positive and negative correlation between atherogenic index (rxy = 0.36) and HDL level (rxy = -0.36) with C-peptide values was found. Differences of HDL, LDL and atherogenic index were, in particular, recorded between the groups below and above the reference range of C-peptide (p ≤ 0.001). Considerable differences (p ≤ 0.001) were also observed for the same lipoprotein characteristics between the groups above and within the C-peptide reference. Generally, the type of cholesterol is crucial for the evaluation of specific changes concerning the C-peptide range. Lipoprotein concentrations differ in relation to C-peptide - not only below and above the physiological range, but also inside and outside of it.

• MeSH
• ateroskleróza epidemiologie   metabolismus   MeSH
• C-peptid * analýza   metabolismus   MeSH
• dospělí MeSH
• krevní glukóza analýza   metabolismus   MeSH
• LDL-cholesterol analýza   metabolismus   MeSH
• lidé středního věku MeSH
• lidé MeSH
• mladiství MeSH
• mladý dospělý MeSH
• omezení příjmu potravy krev   metabolismus   MeSH
• průřezové studie statistika a číselné údaje   MeSH
• senioři MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mladiství MeSH
• mladý dospělý MeSH
• senioři MeSH
• Publikační typ
• práce podpořená grantem MeSH