První vydání 167 stran ; 30 cm
Vysokoškolská učebnice, která se zaměřuje na latinu a lékařské termíny. Určeno studujícím bakalářských zdravotnických oborů.
- Klíčová slova
- latina,
- MeSH
- lékařství MeSH
- terminologie jako téma MeSH
- Konspekt
- Latina
- Učební osnovy. Vyučovací předměty. Učebnice
- NLK Obory
- lingvistika, lékařská terminologie
- NLK Publikační typ
- učebnice vysokých škol
- Publikační typ
- abstrakt z konference MeSH
- Publikační typ
- abstrakt z konference MeSH
- Publikační typ
- abstrakt z konference MeSH
- MeSH
- fyzioterapie (techniky) MeSH
- lidé MeSH
- skolióza * diagnostické zobrazování rehabilitace terapie MeSH
- Check Tag
- lidé MeSH
AIM: The aim of this study was to evaluate the clinical contribution of protein induced by vitamin K absence (PIVKA-II) for hepatocellular carcinoma (HCC) diagnostics and compare it with alpha-foetoprotein (AFP), a routinely used tumour marker. MATERIALS AND METHODS: A total of 332 participants were enrolled in this study: 64 with HCC, 48 with liver metastases of colorectal cancer origin, 42 with liver cirrhosis and 178 healthy individuals. Serum levels of PIVKA-II were measured using the chemiluminescent assay of the Architect 1000i System (Abbott, USA) and AFP levels using the chemiluminescent assay by DxI 800 (Beckman Coulter, USA). RESULTS: PIVKA-II achieved better clinical sensitivity than AFP and the difference in this sensitivity was statistically significant. PIVKA-II achieved the best sensitivity (96.9%) in distinguishing between the HCC and control groups with the proposed cut-off value of 60 mAU/ml. CONCLUSION: Our recommendation is for addition of PIVKA-II to the routine panel of HCC tumour markers.
- MeSH
- biologické markery krev MeSH
- diferenciální diagnóza MeSH
- dospělí MeSH
- hepatocelulární karcinom krev genetika patologie MeSH
- jaterní cirhóza krev genetika patologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- nádorové biomarkery krev MeSH
- nádory jater krev genetika patologie MeSH
- pilotní projekty MeSH
- proteinové prekurzory krev genetika MeSH
- protrombin genetika MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
PURPOSE OF THE STUDY The purpose of the prospective randomised study was to assess the benefits of the platelet-rich fibrin (PRF) application during the anatomic anterior cruciate ligament reconstruction (ACLR) for tendon graft healing. MATERIAL AND METHODS The study included 40 patients with an isolated rupture of the anterior cruciate ligament in the knee. The MRI findings on the tendon graft were evaluated at 6 months and 12 months after the surgery in a total of 33 patients, namely in 10 women/23 men (21 right knee/12 left knee), with the mean age of 29.1 years and at the mean follow-up of 15.9 weeks after the injury. The randomisation using envelopes was carried out at the beginning of arthroscopy either in the group with the PRF application (Group 1) (17 patients) or in the group without the PRF application (Group 2) (16 patients). The followed-up patients underwent the ACLR with targeting the femoral tunnel through anteromedial portal using the autografts of m. semitendinosusand m. graciliswith Tightrope femoral fixation and Inion implant in tibia. In Group 1, during the surgery PRF was applied both in the drilled tunnels (intraosseously) and directly to the surface of the tendon graft itself (intraarticular part). The Group 2 was a control group in which the same intervention was performed, however without the PRF application. In the 6 th and 12 th month after the surgery, the signal intensity of the knee and occurrence of the ACL graft failure, bone (marrow) oedema rate near the tunnels were assessed by an independent radiologist using a 3 Tesla MRI. RESULTS In the 6 th and also in the 12 th postoperative month, neither a complete, nor a partial graft failure was found in the group with PRF, whereas in Group 2 a complete or a partial graft failure was observed in 12.5% (p = 0.23). In the 6th month, a bone marrow oedema near the intraosseous parts of the graft was reported in 94.1% of patients in Group 1 and in 81.3% of patients in Group 2, while in the 12 th month it was 23.5% of evaluated patients in Group 1 and 37.5% patients in Group 2. The differences between the two groups were not statistically significant in the 6 th (p = 0.096) or in the 12 th month (p = 0.43). In the 6 th month, a fully ligamentised graft was found in 52.9% of patients in Group 1 and in 37.5% of patients in Group 2 (p = 0.061), a partially ligamentised graft was present in 47.1% of patients in Group 1 and in 50% of patients in Group 2. In the 12 th month, a fully ligamentised graft was seen in 94.1% of patients in Group 1 and in 75% of patients in Group 2 (p = 0.26) and a partially ligamentised graft was present in 5.9% of patients in Group 1 and in 12.5% of patients in Group 2. In the remaining 12.5% of patients in Group 2, the finding was assessed as a graft with no signs of ligamentisation. DISCUSSION We have not encountered a paper in the Czech or world literature which would present results of a similar study, i.e. which would evaluate the potential benefits of the platelet-rich fibrin application in the course of the anatomic anterior cruciate ligament reconstruction. Majority of studies evaluate the benefits of the application of platelet-rich plasma aimed to achieve a positive effect on the LCA graft healing. CONCLUSIONS Our study proved a higher percentage of ligamentisation and healed grafts into the bone as well as a lower occurrence of graft failure in the group with PRF compared to the group without the PRF application, namely both in the 6 th and in the 12 th month. Nonetheless, the differences between the two groups assessed at the same time were not statistically significant. Key words: anterior cruciate ligament, arthroscopy, anatomic ACL reconstruction, magnetic resonance imaging of the graft, platelet-rich fibrin, graft healing, MRI signal intensity of the graft.
- MeSH
- artroskopie MeSH
- autologní transplantace MeSH
- dospělí MeSH
- femur chirurgie MeSH
- fibrin bohatý na krevní destičky fyziologie MeSH
- kolenní kloub diagnostické zobrazování patologie chirurgie MeSH
- lidé MeSH
- ligamentum cruciatum anterius patologie MeSH
- magnetická rezonanční tomografie metody MeSH
- plazma bohatá na destičky fyziologie MeSH
- poranění předního zkříženého vazu diagnostické zobrazování chirurgie MeSH
- prospektivní studie MeSH
- rejekce štěpu patologie MeSH
- rekonstrukce předního zkříženého vazu metody MeSH
- ruptura patologie MeSH
- šlachy diagnostické zobrazování transplantace MeSH
- tibie chirurgie MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- randomizované kontrolované studie MeSH
- Geografické názvy
- Česká republika MeSH
1. vydání 77 stran : ilustrace ; 30 cm
Studijní materiál s ucelenými informacemi o problematice a významu pánevního dna. Na první anatomické kapitoly, včetně obrazové dokumentace, navazují části diagnostické a terapeutické z pohledu fyzioterapeutické a ošetřovatelské péče.
1. vyd. 158 s. ; 30 cm
- Klíčová slova
- latina,
- MeSH
- lékařství MeSH
- terminologie jako téma MeSH
- Konspekt
- Latina
- Učební osnovy. Vyučovací předměty. Učebnice
- NLK Obory
- lingvistika, lékařská terminologie
- lékařství
- NLK Publikační typ
- učebnice vysokých škol
1. vyd. 167 s. ; 30 cm
- Klíčová slova
- latina,
- MeSH
- lékařství MeSH
- lingvistika MeSH
- terminologie jako téma MeSH
- Konspekt
- Latina
- Učební osnovy. Vyučovací předměty. Učebnice
- NLK Obory
- lingvistika, lékařská terminologie
- lékařství
- pedagogika
- NLK Publikační typ
- učebnice vysokých škol
