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Autor
Aurelian, Rosca 1 Ađić, Filip 1 Ađić, Nada Čemerlić 1 Benedek, Imre 1 Benedek, Theodora 1 Berry, Colin 1 Bosserdt, Maria 1 Boussoussou, Melinda 1 Calabria, Hug Cuéllar 1 Danesh, John 1 Davis, Gershan 1 Delles, Christian 1 Dewey, Marc 1 Diez, Ignacio 1 Dodd, Jonathan D 1 Donnelly, Patrick 1 Dreger, Henryk 1 Drosch, Tanja 1 Erglis, Andrejs 1 Estrella, Melanie 1
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Pracoviště
Administrative Centre Health Care Dis... 1 Bavarian Cancer Registry Bavarian Hea... 1 Berlin Institute of Health at Charité... 1 Berlin University Alliance Berlin Ger... 1 Center of Advanced Research in Multim... 1 Centro de Investigacion Biomedica en ... 1 County Clinical Emergency Hospital Ta... 1 Department of Biomedical Sciences Hum... 1 Department of Cardiology Aintree Univ... 1 Department of Cardiology Alb Fils Kli... 1 Department of Cardiology Basurto Hosp... 1 Department of Cardiology Centro Hospi... 1 Department of Cardiology Copenhagen U... 1 Department of Cardiology George Emil ... 1 Department of Cardiology Herlev Gento... 1 Department of Cardiology Hospital Uni... 1 Department of Cardiology Hospital of ... 1 Department of Cardiology Institute fo... 1 Department of Cardiology Internal Med... 1 Department of Cardiology Liverpool Un... 1
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Autor
Aurelian, Rosca 1 Ađić, Filip 1 Ađić, Nada Čemerlić 1 Benedek, Imre 1 Benedek, Theodora 1 Berry, Colin 1 Bosserdt, Maria 1 Boussoussou, Melinda 1 Calabria, Hug Cuéllar 1 Danesh, John 1 Davis, Gershan 1 Delles, Christian 1 Dewey, Marc 1 Diez, Ignacio 1 Dodd, Jonathan D 1 Donnelly, Patrick 1 Dreger, Henryk 1 Drosch, Tanja 1 Erglis, Andrejs 1 Estrella, Melanie 1
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Pracoviště
Administrative Centre Health Care Dis... 1 Bavarian Cancer Registry Bavarian Hea... 1 Berlin Institute of Health at Charité... 1 Berlin University Alliance Berlin Ger... 1 Center of Advanced Research in Multim... 1 Centro de Investigacion Biomedica en ... 1 County Clinical Emergency Hospital Ta... 1 Department of Biomedical Sciences Hum... 1 Department of Cardiology Aintree Univ... 1 Department of Cardiology Alb Fils Kli... 1 Department of Cardiology Basurto Hosp... 1 Department of Cardiology Centro Hospi... 1 Department of Cardiology Copenhagen U... 1 Department of Cardiology George Emil ... 1 Department of Cardiology Herlev Gento... 1 Department of Cardiology Hospital Uni... 1 Department of Cardiology Hospital of ... 1 Department of Cardiology Institute fo... 1 Department of Cardiology Internal Med... 1 Department of Cardiology Liverpool Un... 1
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- Benedek, Theodora
- Wieske, Viktoria
- Szilveszter, Bálint
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Kofoed, Klaus F
Autor Kofoed, Klaus F Department of Cardiology, Nordsjællands Hospital, University of Copenhagen, Hillerød, Denmark Department of Radiology, Copenhagen University Hospital-Rigshospitalet and Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
- Donnelly, Patrick
- Rodriguez-Palomares, José
- Erglis, Andrejs
- Veselka, Josef
- Šakalytė, Gintarė
- Ađić, Nada Čemerlić
Open Access Digital Library od 1978-01-01 do Před 6 měsíci
Open Access Digital Library od 2000-01-01 do Před 6 měsíci
Medline Complete (EBSCOhost) od 1978-01-01
PubMed
37725834
DOI
10.2337/dc23-0710
Knihovny.cz E-zdroje
OBJECTIVE: To compare cardiac computed tomography (CT) with invasive coronary angiography (ICA) as the initial strategy in patients with diabetes and stable chest pain. RESEARCH DESIGN AND METHODS: This prespecified analysis of the multicenter DISCHARGE trial in 16 European countries was performed in patients with stable chest pain and intermediate pretest probability of coronary artery disease. The primary end point was a major adverse cardiac event (MACE) (cardiovascular death, nonfatal myocardial infarction, or stroke), and the secondary end point was expanded MACE (including transient ischemic attacks and major procedure-related complications). RESULTS: Follow-up at a median of 3.5 years was available in 3,541 patients of whom 557 (CT group n = 263 vs. ICA group n = 294) had diabetes and 2,984 (CT group n = 1,536 vs. ICA group n = 1,448) did not. No statistically significant diabetes interaction was found for MACE (P = 0.45), expanded MACE (P = 0.35), or major procedure-related complications (P = 0.49). In both patients with and without diabetes, the rate of MACE did not differ between CT and ICA groups. In patients with diabetes, the expanded MACE end point occurred less frequently in the CT group than in the ICA group (3.8% [10 of 263] vs. 8.2% [24 of 294], hazard ratio [HR] 0.45 [95% CI 0.22-0.95]), as did the major procedure-related complication rate (0.4% [1 of 263] vs. 2.7% [8 of 294], HR 0.30 [95% CI 0.13 - 0.63]). CONCLUSIONS: In patients with diabetes referred for ICA for the investigation of stable chest pain, a CT-first strategy compared with an ICA-first strategy showed no difference in MACE and may potentially be associated with a lower rate of expanded MACE and major procedure-related complications.
- MeSH
- bolesti na hrudi MeSH
- CT angiografie MeSH
- diabetes mellitus * epidemiologie MeSH
- koronární angiografie metody MeSH
- lidé MeSH
- nemoci koronárních tepen * diagnostické zobrazování MeSH
- počítačová rentgenová tomografie MeSH
- prediktivní hodnota testů MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- multicentrická studie MeSH
- práce podpořená grantem MeSH
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