Human parvovirus 4 (PARV4, family Parvoviridae, genus Tetraparvovirus) displays puzzling features, such as uncertain clinical importance/significance, unclear routes of transmission, and discontinuous geographical distribution. The origin, or the general reservoir, of human PARV4 infection is unknown. We aimed to detect and characterize PARV4 virus in faecal samples collected from two wild chimpanzee populations and 19 species of captive non-human primates. We aimed to investigate these species as a potential reservoir and alternate route of transmission on the African continent. From almost 500 samples screened, a single wild Pan troglodytes schweinfurthii sample tested positive. Full genome analysis, as well as single ORF phylogenies, confirmed species-specific PARV4 infection.
- MeSH
- divoká zvířata virologie MeSH
- feces virologie MeSH
- fylogeneze MeSH
- genom virový MeSH
- infekce viry z čeledi Parvoviridae přenos veterinární virologie MeSH
- nemoci primátů přenos virologie MeSH
- otevřené čtecí rámce MeSH
- Pan troglodytes MeSH
- Parvovirinae klasifikace genetika izolace a purifikace MeSH
- zvířata MeSH
- Check Tag
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
