A 1000-cow study across four European countries was undertaken to understand to what extent ruminant microbiomes can be controlled by the host animal and to identify characteristics of the host rumen microbiome axis that determine productivity and methane emissions. A core rumen microbiome, phylogenetically linked and with a preserved hierarchical structure, was identified. A 39-member subset of the core formed hubs in co-occurrence networks linking microbiome structure to host genetics and phenotype (methane emissions, rumen and blood metabolites, and milk production efficiency). These phenotypes can be predicted from the core microbiome using machine learning algorithms. The heritable core microbes, therefore, present primary targets for rumen manipulation toward sustainable and environmentally friendly agriculture.

• MeSH
• bachor metabolismus   MeSH
• fenotyp MeSH
• fylogeneze MeSH
• kohortové studie MeSH
• krev metabolismus   MeSH
• methan metabolismus   MeSH
• mléko metabolismus   MeSH
• skot genetika   mikrobiologie   MeSH
• střevní mikroflóra genetika   fyziologie   MeSH
• zvířata MeSH
• Check Tag
• skot genetika   mikrobiologie   MeSH
• ženské pohlaví MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH