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Krell-Roesch, Janina
Autor Krell-Roesch, Janina Institute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany (Krell-Roesch, Bezold, Trautwein, Barisch-Fritz, Jekauc, Woll) Department of Quantitative Health Sciences (Krell-Roesch, Syrjanen, Kremers, Vassilaki), Department of Psychiatry and Psychology (Fields), and Department of Neurology (Scharf, Knopman, Petersen), Mayo Clinic, Rochester, Minn International Clinical Research Center, St. Anne University Hospital, Brno, Czech Republic (Stokin) Department of Neurology, Barrow Neurological Institute, Phoenix (Geda)
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Syrjanen, Jeremy A
Autor Syrjanen, Jeremy A Institute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany (Krell-Roesch, Bezold, Trautwein, Barisch-Fritz, Jekauc, Woll) Department of Quantitative Health Sciences (Krell-Roesch, Syrjanen, Kremers, Vassilaki), Department of Psychiatry and Psychology (Fields), and Department of Neurology (Scharf, Knopman, Petersen), Mayo Clinic, Rochester, Minn International Clinical Research Center, St. Anne University Hospital, Brno, Czech Republic (Stokin) Department of Neurology, Barrow Neurological Institute, Phoenix (Geda)
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Bezold, Jelena
Autor Bezold, Jelena Institute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany (Krell-Roesch, Bezold, Trautwein, Barisch-Fritz, Jekauc, Woll) Department of Quantitative Health Sciences (Krell-Roesch, Syrjanen, Kremers, Vassilaki), Department of Psychiatry and Psychology (Fields), and Department of Neurology (Scharf, Knopman, Petersen), Mayo Clinic, Rochester, Minn International Clinical Research Center, St. Anne University Hospital, Brno, Czech Republic (Stokin) Department of Neurology, Barrow Neurological Institute, Phoenix (Geda)
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Trautwein, Sandra
Autor Trautwein, Sandra Institute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany (Krell-Roesch, Bezold, Trautwein, Barisch-Fritz, Jekauc, Woll) Department of Quantitative Health Sciences (Krell-Roesch, Syrjanen, Kremers, Vassilaki), Department of Psychiatry and Psychology (Fields), and Department of Neurology (Scharf, Knopman, Petersen), Mayo Clinic, Rochester, Minn International Clinical Research Center, St. Anne University Hospital, Brno, Czech Republic (Stokin) Department of Neurology, Barrow Neurological Institute, Phoenix (Geda)
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Barisch-Fritz, Bettina
Autor Barisch-Fritz, Bettina Institute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany (Krell-Roesch, Bezold, Trautwein, Barisch-Fritz, Jekauc, Woll) Department of Quantitative Health Sciences (Krell-Roesch, Syrjanen, Kremers, Vassilaki), Department of Psychiatry and Psychology (Fields), and Department of Neurology (Scharf, Knopman, Petersen), Mayo Clinic, Rochester, Minn International Clinical Research Center, St. Anne University Hospital, Brno, Czech Republic (Stokin) Department of Neurology, Barrow Neurological Institute, Phoenix (Geda)
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Kremers, Walter K
Autor Kremers, Walter K Institute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany (Krell-Roesch, Bezold, Trautwein, Barisch-Fritz, Jekauc, Woll) Department of Quantitative Health Sciences (Krell-Roesch, Syrjanen, Kremers, Vassilaki), Department of Psychiatry and Psychology (Fields), and Department of Neurology (Scharf, Knopman, Petersen), Mayo Clinic, Rochester, Minn International Clinical Research Center, St. Anne University Hospital, Brno, Czech Republic (Stokin) Department of Neurology, Barrow Neurological Institute, Phoenix (Geda)
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Fields, Julie A
Autor Fields, Julie A Institute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany (Krell-Roesch, Bezold, Trautwein, Barisch-Fritz, Jekauc, Woll) Department of Quantitative Health Sciences (Krell-Roesch, Syrjanen, Kremers, Vassilaki), Department of Psychiatry and Psychology (Fields), and Department of Neurology (Scharf, Knopman, Petersen), Mayo Clinic, Rochester, Minn International Clinical Research Center, St. Anne University Hospital, Brno, Czech Republic (Stokin) Department of Neurology, Barrow Neurological Institute, Phoenix (Geda)
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Scharf, Eugene L
Autor Scharf, Eugene L Institute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany (Krell-Roesch, Bezold, Trautwein, Barisch-Fritz, Jekauc, Woll) Department of Quantitative Health Sciences (Krell-Roesch, Syrjanen, Kremers, Vassilaki), Department of Psychiatry and Psychology (Fields), and Department of Neurology (Scharf, Knopman, Petersen), Mayo Clinic, Rochester, Minn International Clinical Research Center, St. Anne University Hospital, Brno, Czech Republic (Stokin) Department of Neurology, Barrow Neurological Institute, Phoenix (Geda)
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Knopman, David S
Autor Knopman, David S Institute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany (Krell-Roesch, Bezold, Trautwein, Barisch-Fritz, Jekauc, Woll) Department of Quantitative Health Sciences (Krell-Roesch, Syrjanen, Kremers, Vassilaki), Department of Psychiatry and Psychology (Fields), and Department of Neurology (Scharf, Knopman, Petersen), Mayo Clinic, Rochester, Minn International Clinical Research Center, St. Anne University Hospital, Brno, Czech Republic (Stokin) Department of Neurology, Barrow Neurological Institute, Phoenix (Geda)
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Stokin, Gorazd B
Autor Stokin, Gorazd B Institute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany (Krell-Roesch, Bezold, Trautwein, Barisch-Fritz, Jekauc, Woll) Department of Quantitative Health Sciences (Krell-Roesch, Syrjanen, Kremers, Vassilaki), Department of Psychiatry and Psychology (Fields), and Department of Neurology (Scharf, Knopman, Petersen), Mayo Clinic, Rochester, Minn International Clinical Research Center, St. Anne University Hospital, Brno, Czech Republic (Stokin) Department of Neurology, Barrow Neurological Institute, Phoenix (Geda)
PubMed
36464975
DOI
10.1176/appi.neuropsych.20220068
Knihovny.cz E-zdroje
OBJECTIVE: This study examined associations between physical activity (PA) and neuropsychiatric symptoms (NPS) in older adults free of dementia. METHODS: This cross-sectional study included 3,222 individuals ≥70 years of age (1,655 men; mean±SD age=79.2±5.6; cognitively unimpaired, N=2,723; mild cognitive impairment, N=499) from the population-based Mayo Clinic Study of Aging. PA (taken as a presumed predictor) in midlife (i.e., when participants were 50-65 years of age) and late life (i.e., the year prior to assessment) was assessed with a self-reported, validated questionnaire; PA intensity and frequency were used to calculate composite scores. NPS (taken as presumed outcomes) were assessed with the Neuropsychiatric Inventory Questionnaire, Beck Depression Inventory (BDI-II), and Beck Anxiety Inventory (BAI). Regression analyses included midlife and late-life PA in each model, which were adjusted for age, sex, education, apolipoprotein E ɛ4 status, and medical comorbidity. RESULTS: Higher late-life PA was associated with lower odds of having apathy (OR=0.89, 95% CI=0.84-0.93), appetite changes (OR=0.92, 95% CI=0.87-0.98), nighttime disturbances (OR=0.95, 95% CI=0.91-0.99), depression (OR=0.94, 95% CI=0.90-0.97), irritability (OR=0.93, 95% CI=0.89-0.97), clinical depression (OR=0.92, 95% CI=0.88-0.97), and clinical anxiety (OR=0.90, 95% CI=0.86-0.94), as well as lower BDI-II (β estimate=-0.042, 95% CI=-0.051 to -0.033) and BAI (β estimate=-0.030, 95% CI=-0.040 to -0.021) scores. Higher midlife PA was associated only with higher BDI-II scores (β estimate=0.011, 95% CI=0.004 to 0.019). Sex modified the associations between PA and NPS. CONCLUSIONS: Late-life PA was associated with a lower likelihood of clinical depression or anxiety and subclinical NPS. These findings need to be confirmed in a cohort study.
- MeSH
- cvičení MeSH
- deprese * psychologie MeSH
- kognitivní dysfunkce * diagnóza MeSH
- kohortové studie MeSH
- lidé MeSH
- neuropsychologické testy MeSH
- průřezové studie MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- stárnutí MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- Publikační typ
- časopisecké články MeSH
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