BACKGROUND: Anorectal dysfunction (ARD), especially bowel incontinence, frequently compromises the quality of life in multiple sclerosis (MS) patients. The effect of rehabilitation procedures has not been clearly established. OBJECTIVE: To determine the effect of an individualized rehabilitation approach on bowel incontinence and anorectal pressures. METHODS: MS patients with ARD underwent 6-months of individually targeted biofeedback rehabilitation. High resolution anorectal manometry (HRAM) and St. Mark's Fecal Incontinence Scores (SMIS) were completed prior to rehabilitation, after 10 weeks of supervised physiotherapy, and after 3 months of self-treatment. RESULTS: Ten patients (50%) completed the study. Repeated measures analysis of variance (ANOVA) demonstrated significant improvement in the SMIS questionnaire over time [14.00 baseline vs. 9.70 after supervised physiotherapy vs. 9.30 after self-treatment (p = 0.005)]. No significant improvements over time were noted in any HRAM readings: maximal pressure [49.85 mmHg baseline vs. 57.60 after supervised physiotherapy vs. 60.88 after self-treatment (p = 0.58)], pressure endurance [36.41 vs. 46.89 vs. 49.95 (p = 0.53)], resting pressure [55.83, vs 52.69 vs. 51.84 (p = 0.704)], or area under the curve [230.0 vs. 520.8 vs. 501.9 (p = 0.16)]. CONCLUSIONS: The proposed individualized rehabilitation program supports a positive overall effect on anorectal dysfunction in MS patients.
- MeSH
- biofeedback (psychologie) MeSH
- fekální inkontinence * etiologie MeSH
- kvalita života MeSH
- lidé MeSH
- manometrie MeSH
- pilotní projekty MeSH
- roztroušená skleróza * komplikace MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
Androgenic alopecia (AGA) is a common and chronic condition. It may impact self-esteem, self-image and quality of life. Benefit, tolerability, cosmetic acceptance and patient satisfaction are key to ensure good treatment outcome. Hair loss improvement and hair quality with AC5 (2,4-Diamino-Pyrimidine-N-Oxyde, arginine, 6-O glucose linoleate (SP94), piroctone olamine and Vichy mineralizing water) once daily was assessed in 527 subjects with mild AGA in an open-label, observational, international real-life study. After 3 months, investigators evaluated the impact of AC5 on hair loss, product satisfaction and asked subjects about local tolerance; subjects assessed hair growth and quality and satisfaction. Data from 357 subjects were evaluable for the benefit analysis; 59.9% of subjects were female; the mean age was 33.6±8.7 years. Duration of hair loss was 1.62±2.24 years. 71.3% of women had a Ludwig score of 1 and 40.8% of men had a Hamilton Norwood score of 2. At the end of study, hair loss was reduced in 89.0% of subjects; it was slightly higher in women (92.5%) than in men (83.8%). Subject satisfaction on a scale from 0 (not satisfied at all) to 10 (completely satisfied) was 7.9±1.7. Tolerance was rated good to very good by 98.6% of all subjects. In conclusion, AC5 reduces mild AGA in both men and women with a pleasant texture. AC5 was well tolerated and highly appreciated.
- MeSH
- alopecie * farmakoterapie terapie MeSH
- dospělí MeSH
- kvalita života * MeSH
- lidé MeSH
- mladý dospělý MeSH
- spokojenost pacientů MeSH
- vlasy, chlupy MeSH
- výsledek terapie MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- pozorovací studie MeSH
Součástí terapie roztroušené sklerózy (RS) by měla být i ucelená rehabilitace. Bohužel právě ona je velmi často v praxi opomíjena, přestože o jejím významu již v současné době není pochyb. Článek pojednává o současných možnostech a cílech komplexní rehabilitace, o vhodných pohybových programech, neurofyziologických technikách a o současných moderních rehabilitačních trendech.
Comprehensive rehabilitation should be an important component of multiple sclerosis treatment. Unfortunately, it is often neglected despite its undoubtable importance. The article covers contemporary views of rehabilitation possibilities and aims, appropriate locomotion programs, neurophysiological techniques and modern trends of treatment approaches.
- Klíčová slova
- funkční elektrická stimulace,
- MeSH
- elektrostimulační terapie MeSH
- fyzioterapie (techniky) * MeSH
- kognitivní dysfunkce rehabilitace MeSH
- kognitivní remediace MeSH
- lidé MeSH
- neurologické poruchy chůze rehabilitace terapie MeSH
- onemocnění dna pánevního rehabilitace MeSH
- poruchy polykání rehabilitace MeSH
- posturální rovnováha MeSH
- progrese nemoci MeSH
- reflexní terapie MeSH
- roztroušená skleróza * rehabilitace MeSH
- strečink MeSH
- svalová spasticita farmakoterapie rehabilitace MeSH
- terapie cvičením metody MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- práce podpořená grantem MeSH
- MeSH
- anální atrézie rehabilitace MeSH
- fekální inkontinence rehabilitace MeSH
- lidé MeSH
- onemocnění dna pánevního * diagnóza patofyziologie rehabilitace MeSH
- pánevní bolest rehabilitace MeSH
- pánevní dno fyziologie MeSH
- prolaps pánevních orgánů rehabilitace MeSH
- zácpa rehabilitace MeSH
- Check Tag
- lidé MeSH
- MeSH
- defekace fyziologie MeSH
- fyzioterapie (techniky) * klasifikace MeSH
- lidé MeSH
- močení fyziologie MeSH
- onemocnění dna pánevního * diagnóza dietoterapie klasifikace rehabilitace MeSH
- pánevní dno * anatomie a histologie fyziologie patofyziologie MeSH
- techniky cvičení a pohybu MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- přehledy MeSH
