The paper presents the review of acute intestine infection and hepatitis A disease analysis for urbanized population in selected regions of Kazakhstan. For the study, five different provinces of the country were chosen, varying by the nature of the economic and socio-economic characteristics. Based on the obtained results, we see the incidence of AII as a conditioned by the combined environmental and socio-economic factors. In this regard, the incidence of AII in urbanized territories can serve as nosology for studying influence of this factors.
- MeSH
- hepatitida A * MeSH
- incidence MeSH
- infekční nemoci * MeSH
- lidé MeSH
- nemoci střev * MeSH
- společenská třída * MeSH
- Check Tag
- lidé MeSH
- Geografické názvy
- Kazachstán MeSH
A model of integration of sanitary-epidemiological services, organizations of primary health care (PHC), medical and social services and nongovernmental organizations in the sphere of public health was developed. Its introduction in a pilot region produced positive results in rendering preventive medical services to the public, which are evidenced by the results of a sociological questionnaire survey of the patients and health care providers. The level of medical and social case work with vulnerable social groups of the population increased. The amount of dispensary patients, visiting topical health promoting schools raised from 30.6% to 58.9%, which resulted in reducing the ambulance call-out frequency during the working hours of medical preventive institutions by 2.5 times (from 0.33 to 0.13; p <0.5). The system of infection control was introduced. Epidemiologist's actions enabled arrangement of continuity in epidemiological observation between territorial institutions of PHC and sanitary-epidemiological surveillance.
- MeSH
- lidé MeSH
- veřejné zdravotnictví * MeSH
- Check Tag
- lidé MeSH
- Geografické názvy
- Kazachstán MeSH
In Kazakhstan, studies of bacterial contamination of the territory and its relationship to morbidity of the population have not been conducted so far. In this connection, the study and estimation of biological indicators - markers of the microbial contamination of environmental objects, determination of the causal relationships between revealed factor and state of population health in Kazakhstan becomes important and necessary. Observations were conducted in the towns and villages in five regions of Kazakhstan, which differ by the nature of industrial and agricultural activities.
- MeSH
- Escherichia coli * patogenita MeSH
- infekce vyvolané Escherichia coli * epidemiologie MeSH
- lidé MeSH
- Check Tag
- lidé MeSH
- Geografické názvy
- Kazachstán MeSH
Light form of disease flow was observed in 69.3% (9/13) among the patients with acute hepatitis C, and in 77.8% (7/9) among the patients with non verified hepatitis. Detectability of RNA-HGV consists of 77.8% (7/9) and 42.8% (3/7) correspondingly among the patients' groups with light form of disease. All HGV RNA positive patients had 2 times lower content of total bilirubin and ALT in the blood comparing to RNA-HGV negative patients. HGV showed an active (4.7 EA) ability to induce the interferon formation. The C G hepatitis patients had interferon titer equal to 3.7 EA, which apparently provides relief of hepatitis C clinical picture.
- MeSH
- biochemická analýza krve * MeSH
- hepatitida C * patologie MeSH
- lidé MeSH
- RNA virová krev MeSH
- virus GB-C * MeSH
- Check Tag
- lidé MeSH
The analysis of epidemiological and etiological characteristics in leading forms of acute enteric infections among the population of Kazakhstan is carried out. The age, social and professional factors in development of epidemic process and intestinal infections were observed. 425 tests of feces of persons of various age groups with intestines dysfunction were investigated. Seromonitoring among inhabitants of Almaty and Almaty area by erythrocyte diagnosticum with salmonelesis serogroups A, B, C, D, Е and rare (О-24). Dynamics in occurrence of salmonella antibodies during months of the year was studied.
The work provides experimental research of bacteria Escherichia coli interferon producing ability. The dynamic accumulation of interferon in growing cells and organ cultures of mice was studied. It is shown that introduction Escherichia coli in the serum and organ cells of mice causes formation of endogenous interferon which is capable to protect of mice from a lethal virus infection. Experiments were undertaken for the purpose of expansion of a spectrum of studies on immunological mechanism development during the interaction with bacteria and viruses and for data acquisition about interferon reactions of organism in response to action intestinal of bacteria Escherichia coli.
- MeSH
- biochemická analýza krve MeSH
- Escherichia coli izolace a purifikace MeSH
- infekce vyvolané Escherichia coli * imunologie krev MeSH
- interferony fyziologie MeSH
- kultivované buňky * MeSH
- laboratoře MeSH
- lidé MeSH
- modely nemocí na zvířatech MeSH
- myši MeSH
- výzkumný projekt MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- myši MeSH
- zvířata MeSH
