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Autor
Bielniková-Kryštofová, Hana 1 Brisudová, Aneta 1 Fritzová, Dominika 1 Jakubec, Petr 1 Katuchová, Vladimíra 1 Klein, JIří 1 Kolář, Zdeněk 1 Michálek, Jaroslav 1 Mitták, Marcel 1 Motyka, Oldřich 1 Ponikelská, Natálie 1 Raclavský, Vladislav 1 Rozsivalová, Denisa 1 Skanderová, Daniela 1 Skopelidou, Valeria 1 Szkorupa, Marek 1 Škarda, Jozef 1 Švecová, Petra 1
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Pracoviště
Department of Clinical and Molecular ... 1 Department of Microbiology Faculty of... 1 Department of Respiratory Diseases Fa... 1 Department of Surgery 1 Faculty of Me... 1 Department of Surgical Studies Univer... 1 Faculty of Medicine University of Ost... 1 Faculty of Mining and Geology VŠB Tec... 1 Institute of Molecular and Clinical P... 1 Nanotechnology Centre CEET VŠB Techni... 1 Surgical Clinic Thomas Bat'a Regional... 1
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Autor
Bielniková-Kryštofová, Hana 1 Brisudová, Aneta 1 Fritzová, Dominika 1 Jakubec, Petr 1 Katuchová, Vladimíra 1 Klein, JIří 1 Kolář, Zdeněk 1 Michálek, Jaroslav 1 Mitták, Marcel 1 Motyka, Oldřich 1 Ponikelská, Natálie 1 Raclavský, Vladislav 1 Rozsivalová, Denisa 1 Skanderová, Daniela 1 Skopelidou, Valeria 1 Szkorupa, Marek 1 Škarda, Jozef 1 Švecová, Petra 1
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Pracoviště
Department of Clinical and Molecular ... 1 Department of Microbiology Faculty of... 1 Department of Respiratory Diseases Fa... 1 Department of Surgery 1 Faculty of Me... 1 Department of Surgical Studies Univer... 1 Faculty of Medicine University of Ost... 1 Faculty of Mining and Geology VŠB Tec... 1 Institute of Molecular and Clinical P... 1 Nanotechnology Centre CEET VŠB Techni... 1 Surgical Clinic Thomas Bat'a Regional... 1
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- Kategorie
- Jazyk
- Země
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Free Medical Journals od 2004
PubMed Central od 2018
ProQuest Central od 2004-01-01
Sciendo od 2022-06-30
ROAD: Directory of Open Access Scholarly Resources od 2004
PubMed
38103007
DOI
10.33073/pjm-2023-044
Knihovny.cz E-zdroje
Lung malignancies have a substantial impact on cancer incidence and mortality worldwide. Even though many factors involved in the development of the disease are known, many questions remain unanswered. Previous studies suggest that the intestinal microbiota may have a role in developing malignant diseases. According to some findings, the microbiota has proven to be a key modulator of carcinogenic processes and the immune response against cancer cells, potentially influencing the effectiveness of immunotherapy. In our study, we characterized culturable microorganisms associated with non-small cell lung cancer (NSCLC) that can be recovered from rectal swabs and mouthwash. In addition, we also explored differences in the culturable microbiota with two main types of NSCLC - adenocarcinoma (ADC) and squamous cell carcinoma (SCC). With 141 patients included in the study (86 ADC and 55 SCC cases), a significant difference was observed between the two types in seven bacterial species (Collinsella, Corynebacterium, Klebsiella, Lactobacillus, Neisseria, Rothia, and Streptococcus), including the site of origin. The relationship between microbial dysbiosis and lung cancer is poorly understood; future research could shed light on the links between gut microbiota and lung cancer development.
- MeSH
- adenokarcinom * MeSH
- lidé MeSH
- mikrobiota * MeSH
- nádory plic * mikrobiologie patologie MeSH
- nemalobuněčný karcinom plic * mikrobiologie patologie MeSH
- spinocelulární karcinom * MeSH
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- lidé MeSH
- Publikační typ
- časopisecké články MeSH
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