UNLABELLED: It has been shown that HIV-positive haemophilic children develop growth retardation. As not only the HIV infection but also other disease-related factors might compromise growth in these children, growth data were analysed in a longitudinal cross-sectional manner in 84 HIV-negative haemophilic patients from two university clinics. A total of 2-24 height and weight measurements (median 6) were recorded in each patient resulting in 683 single values collected between 1977-1995. Height SDS of all haemophilic boys was -0.31 +/- 2.13 (mean +/- SD, NS versus 0) and body mass index SDS was 0.21 +/- 3.49 (mean SD, NS versus 0) at first measurement and remained unchanged throughout the observation period. Neither height nor body mass index differed with respect to the severity of haemophilia (mild/moderate/severe) or the study centre (Vienna/Prague). CONCLUSION: Growth in HIV-negative patients with haemophilia is not affected in spite of the immunological abnormalities attributed to the substitution therapy or the bleeding episodes in the joints with the potential effect on the growth plate.
- MeSH
- dítě MeSH
- dospělí MeSH
- hemofilie A klasifikace komplikace terapie MeSH
- HIV séronegativita * MeSH
- index tělesné hmotnosti MeSH
- kojenec MeSH
- lidé MeSH
- lineární modely MeSH
- longitudinální studie MeSH
- mladiství MeSH
- poruchy růstu diagnóza etiologie imunologie MeSH
- předškolní dítě MeSH
- průřezové studie MeSH
- studie případů a kontrol MeSH
- stupeň závažnosti nemoci MeSH
- tělesná hmotnost MeSH
- tělesná výška MeSH
- Check Tag
- dítě MeSH
- dospělí MeSH
- kojenec MeSH
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- předškolní dítě MeSH
- Publikační typ
- časopisecké články MeSH
