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Influence of COX-2-induced PGE2 on the initiation and progression of tail regeneration in Northern House Gecko, Hemidactylus flaviviridis
P. Sharma, B. Suresh
Jazyk angličtina Země Česko
NLK
Free Medical Journals
od 2000
Freely Accessible Science Journals
od 2000
ProQuest Central
od 2005-01-01
Health & Medicine (ProQuest)
od 2005-01-01
ROAD: Directory of Open Access Scholarly Resources
od 2000
- MeSH
- cyklooxygenasa 2 biosyntéza MeSH
- dinoproston antagonisté a inhibitory fyziologie MeSH
- inhibitory cyklooxygenasy farmakologie MeSH
- ještěři fyziologie MeSH
- ocas fyziologie účinky léků MeSH
- pyrazoly farmakologie MeSH
- pyridiny farmakologie MeSH
- regenerace fyziologie účinky léků MeSH
- sulfonamidy farmakologie MeSH
- sulfony farmakologie MeSH
- zvířata MeSH
- Check Tag
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- zvířata MeSH
We investigated the role of prostaglandin E2 in reptilian regeneration. Prostaglandin E2 is known to play a vital role during wound healing and cell proliferation. A significant delay in the rate of growth of regenerate after autotomy was observed when the production of prostaglandin E2 was blocked by usage of specific cyclooxygenase inhibitors as compared to control animals and this delay continued to all the defined stages of regeneration. Therefore, prostaglandin E2 could be one of the essential requirements for a successful process of regeneration.
Lit.: 39
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- $a We investigated the role of prostaglandin E2 in reptilian regeneration. Prostaglandin E2 is known to play a vital role during wound healing and cell proliferation. A significant delay in the rate of growth of regenerate after autotomy was observed when the production of prostaglandin E2 was blocked by usage of specific cyclooxygenase inhibitors as compared to control animals and this delay continued to all the defined stages of regeneration. Therefore, prostaglandin E2 could be one of the essential requirements for a successful process of regeneration.
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