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Cellulolytic thermophilic microorganisms in white biotechnology: a review
K. Sahoo, RK. Sahoo, M. Gaur, E. Subudhi,
Jazyk angličtina Země Spojené státy americké
Typ dokumentu časopisecké články, přehledy
Grantová podpora
YSS/2014/000413
Science and Engineering Research Board
- MeSH
- Bacteria enzymologie genetika metabolismus MeSH
- celulasa genetika MeSH
- celulosa metabolismus MeSH
- enzymy MeSH
- genetické inženýrství MeSH
- metabolické inženýrství * MeSH
- metagenomika MeSH
- průmyslová mikrobiologie metody MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
Enzymes of microbial origin are of immense importance for organic material decomposition leading to bioremediation of organic waste, bioenergy generation, large-scale industrial bioprocesses, etc. The market demand for microbial cellulase enzyme is growing more rapidly which ultimately becomes the driving force towards research on this biocatalyst, widely used in various industrial activities. The use of novel cellulase genes obtained from various thermophiles through metagenomics and genetic engineering as well as following metabolic engineering pathways would be able to enhance the production of thermophilic cellulase at industrial scale. The present review is mainly focused on thermophilic cellulolytic bacteria, discoveries on cellulase gene, genetically modified cellulase, metabolic engineering, and their various industrial applications. A lot of lacunae are yet to overcome for thermophiles such as metagenome analysis, metabolic pathway modification study, search of heterologous hosts in gene expression system, and improved recombinant strain for better cellulase yield as well as value-added product formation.
Citace poskytuje Crossref.org
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