Skin and soft-tissue infections (SSTIs) encompass a variety of pathological conditions that involve the skin and underlying subcutaneous tissue, fascia, or muscle, ranging from simple superficial infections to severe necrotizing infections. SSTIs are a frequent clinical problem in surgical departments. In order to clarify key issues in the management of SSTIs, a task force of experts met in Bertinoro, Italy, on June 28, 2018, for a specialist multidisciplinary consensus conference under the auspices of the World Society of Emergency Surgery (WSES) and the Surgical Infection Society Europe (SIS-E). The multifaceted nature of these infections has led to a collaboration among general and emergency surgeons, intensivists, and infectious disease specialists, who have shared these clinical practice recommendations.

1st Department of Surgery Department of Abdominal Thoracic Surgery and Traumatology 1st Faculty of Medicine Charles University and General University Hospital Prague Czech Republic

2nd Department of Surgery Aretaieion University Hospital National and Kapodistrian University of Athens Athens Greece

2nd Department of Surgery Hospital de Clínicas Universidad Nacional de Asuncion San Lorenzo Paraguay

Abdominal Center University Hospital Meilahti Helsinki Finland

Anesthesiology and Critical Care Medicine Paris Diderot Sorbonne Cite University Bichat Claude Bernard University Hospital HUPNSV Paris France

Department of Anesthesia and Intensive Care Azienda Ospedaliero Universitaria Parma Parma Italy

Department of Emergency Surgery City Hospital Mozyr Belarus

Department of Emergency Surgery Parma Maggiore Hospital Parma Italy

Department of General and Emergency Surgery Riga East University Hospital 'Gailezers' Riga Latvia

Department of General Surgery Division of Surgery Rambam Health Care Campus Haifa Israel

Department of Medical Sciences Infectious Diseases University of Turin Turin Italy

Department of Surgery Academic Medical Centre Amsterdam Netherlands

Department of Surgery Addenbrooke's Hospital Cambridge University Hospitals NHS Foundation Trust Cambridge UK

Department of Surgery Anadolu Medical Center Kocaali Turkey

Department of Surgery College of Medicine and Health Sciences UAE University Al Ain United Arab Emirates

Department of Surgery Emergency Hospital of Bucharest Bucharest Romania

Department of Surgery Letterkenny University Hospital and Donegal Clinical Research Academy Letterkenny Ireland

Department of Surgery Macerata Hospital Macerata Italy

Department of Surgery UMC Ljubljana Ljubljana Slovenia

Department of Surgery University of Colorado Denver Health Medical Center Denver CO USA

Department of Surgical Disciplines Immanuel Kant Baltic Federal University Regional Clinical Hospital Kaliningrad Russian Federation

Emergency Surgery Fondazione Policlinico Universitario A Gemelli IRCCS Università Cattolica del Sacro Cuore Rome Italy

Emergency Surgery Unit State University of Pisa Cisanello Hospital Pisa Italy

General Surgery Department Bufalini Hospital Cesena Italy

General Surgery Department Colorectal Surgery Unit La Paz University Hospital Madrid Spain

General Surgery Department Medical University University Hospital St George Plovdiv Bulgaria

General Surgery Tan Tock Seng Hospital Singapore Singapore

General Surgery Trauma Team State University of Milano Niguarda Hospital Milano Milan Italy

Global Alliance for Infections in Surgery Porto Portugal

Infectious Diseases Division Department of Medicine University of Udine and Azienda Sanitaria Universitaria Intergrata di Udine Udine Italy

Infectious Diseases Unit Bolzano Central Hospital Bolzano Italy

Infectious Diseases Unit Department of Medical and Surgical Sciences Alma Mater Studiorum University of Bologna Bologna Italy

Riverside University Health System Medical Center and Loma Linda University School of Medicine Moreno Valley CA USA

Trauma and Acute Care Surgery Scripps Memorial Hospital La Jolla La Jolla CA USA

Trauma Service Inkosi Albert Luthuli Central Hospital and Department of Surgery Nelson R Mandela School of Clinical Medicine Durban South Africa

Unit of Endocrine Head and Neck Surgery and Unit of Surgical Infections Support Department of General Surgery Parc Taulí Hospital Universitari Sabadell Spain

Unit of General Emergency and Trauma Surgery Regional Hospital of Perpignan Perpignan France

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