INTRODUCTION: Primary breast sarcoma is a very rare malignant type of breast tumours with an incidence of 0.1% of all primary breast malignancies. METHODS: We present a retrospective analysis of the case series from two hospitals in the Czech Republic with a review of the diagnostic and treatment approach to primary breast sarcomas with an analysis of published prognostic factors. RESULTS: Eleven patients were included in the study, 9 women and 2 men. Statistical evaluation revealed that tumour size (p = 0.1964), grade (p = 0.1667), margin distance (p = 0.5403), mitotic activity (p = 0.8577), or age (p = 0.7822) were not prognostic factors in our cohort. CONCLUSION: The analysis did not prove any of the factors, such as age, tumour size, grade, or mitotic activity, to be statistically significant prognostic factors. Based on the literature review, the most common published prognostic factors are tumour size, margin status, and grade, but the results are ambiguous.

Department of Comprehensive Cancer Care Faculty of Medicine Masaryk University Brno Czech Republic

Department of Comprehensive Cancer Care Masaryk Memorial Cancer Institute Brno Czech Republic

Department of Pathology Masaryk Memorial Cancer Institute Brno Czech Republic

Department of Pathology Silesian Hospital in Opava Opava Czech Republic

Department of Radiation Oncology Faculty of Medicine Masaryk University Brno Czech Republic

Department of Radiation Oncology Masaryk Memorial Cancer Institute Brno Czech Republic

Department of Surgery Silesian Hospital in Opava Opava Czech Republic

Department of Surgical Oncology Faculty of Medicine Masaryk University Brno Czech Republic

Department of Surgical Oncology Masaryk Memorial Cancer Institute Brno Czech Republic

The Institute of Paramedical Health Studies Faculty of Public Policies Silesian University Opava Czech Republic

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