120 stran : ilustrace, tabulky
Presentation of the myeloproliferative neoplasms (MPNs) varies widely, and correct diagnosis and management can be challenging, and is becoming more complex as understanding of the underlying molecular basis for these disorders emerges. Appropriate management is increasingly informed by accurate risk stratification founded on understanding of cytogenetic and molecular markers, as well as the clinical presentation.'Fast Facts: myeloproliferative neoplasms' focuses on the three most common chronic MPNs:• Essential thrombocythemia (ET) – characterized by increased platelet count• Polycythemia vera (PV) – characterized by excessive production of red blood cells• Primary myelofibrosis – a more severe and heterogenous disorder that may overlap with ET and PV but is commonly associated with anemia.Written by two leading experts in the field, Fast Facts: myeloproliferative neoplasms provides concise, up-to-date and practical guidance on the accurate diagnosis, risk stratification and management of these MPNs. It also provides key insights into our growing understanding of the underlying molecular and genetic basis of these disorders, and how this is informing risk stratification and management strategies. This concise handbook will be invaluable to clinicians, medical students, nurses, pharmacists and scientists in understanding and overcoming the everyday and rarer challenges associated with MPN.
7 stran : ilustrace, tabulky ; 30 cm
- Klíčová slova
- Anagrelid, Xagrid, Thromboreductin,
- MeSH
- esenciální trombocytemie MeSH
- farmakoterapie MeSH
- generika MeSH
- náhrada léků MeSH
- zákonodárství farmaceutické MeSH
- Konspekt
- Farmacie. Farmakologie
- NLK Obory
- farmacie a farmakologie
- NLK Publikační typ
- brožury
- separáty
Závěrečná zpráva o řešení grantu Interní grantové agentury MZ ČR
Přeruš. str. : il., tab. ; 30 cm
Annotation 1 The retrospective study of paediatric patients with myeloproliferative diseases in the Czech Republic diagnosed between 1986-2005, molecular-genetic analysis of JAK2, TPO, c-mpl gene mutations, PRV-1 gene expression and clonality. Annotation2 The aim of the study is better understanding of pathophysiology of the myeloproliferative diseases in childhood, improvement of diagnostic and treatment standards as well as the quality of life, initiation of international cooperation.
Anotace 1 Předmětem projektu je analýza výskytu a etiopatogeneze myeloproliferativních chorob (MPDs) u dětí s výjimkou CML. Metody: retrospektivní analýza všech případů MPDs v dětské populaci České republiky za posledních 20 let. Anotace 2 U všech pacientů bude provedeno vyšetření růstu erytroidních kolonií, citlivosti na erytropoetin, analýza mutací genu pro JAK2 kinázu, trombopoetin a jeho receptor, VHL, receptor pro erytropoetin, exprese PRV-1 genu, klonality u dívek. Anotace 3 Cílem projektu je zlepšení úrovně diagnostiky a standardizace léčebné péče o dětské pacienty s MPDs.
- MeSH
- dítě MeSH
- erythropoetin MeSH
- esenciální trombocytemie MeSH
- myeloproliferativní poruchy diagnóza terapie MeSH
- polycytemie MeSH
- thrombopoetin MeSH
- Check Tag
- dítě MeSH
- Konspekt
- Pediatrie
- NLK Obory
- pediatrie
- hematologie a transfuzní lékařství
- NLK Publikační typ
- závěrečné zprávy o řešení grantu IGA MZ ČR
Seminars in oncology, ISSN 0093-7754 vol. 29, no. 3, suppl. 10, June 2002
32 s. : il., tab. ; 28 cm
