The revised Fourth Edition of this highly acclaimed reference is a practical, state-of-the-art, superbly illustrated guide to the evaluation and clinical correlates of prostate biopsy findings. This edition features expanded coverage of mimickers of prostate cancer, a new chapter on immunohistochemistry and molecular techniques, a major update to the Gleason grading system, new information on histologic changes following radiation therapy, and an expanded section on tumors of specialized prostatic stroma. The book contains nearly 300 full-color illustrations. A companion online image bank provides over 1,800 full-color images of specimens at various magnifications, plus a question-and-answer review of prostate pathology.

Prostate biopsy interpretation

Includes bibliographical references and index.

Clinical correlates with biopsy: serum prostate-specific -- Antigen, digital rectal examination, and imaging techniques -- Needle biopsy technique: tissue sampling and processing of needle -- Biopsy and transurethral resection specimens -- Gross anatomy and normal histology -- Inflammatory conditions -- Prostatic intraepithelial neoplasia and its mimickers -- Diagnosis of limited adenocarcinoma of the prostate -- Mimickers of adenocarcinoma of the prostate -- Reporting cancer: influence on prognosis and treatment -- Grading of prostatic adenocarcinomas -- Findings of atypical glands suspicious for cancer -- Prostatic duct adenocarcinoma -- Neuroendocrine differentiation in the benign and malignant prostate -- Mucinous differentiation in the benign and malignant prostate -- Benign and malignant prostate following treatment -- Urothelial carcinoma -- Mesenchymal tumors and tumor-like conditions -- Miscellaneous benign and malignant lesions -- Prostatic urethral lesions -- Emerging biomarkers for detection and management.