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Bunkové delenie a apoptóza v rostrálnej migračnej dráhe potkana v skorom postnatálnom vývoji [Cell proliferation and apoptosis in the rostral migratory stream of developing rats]
E. Račeková, M. Martončíková, B. Mitrušková
Language English Country Czech Republic
- MeSH
- Apoptosis genetics MeSH
- Cell Division physiology MeSH
- Central Nervous System cytology growth & development MeSH
- Research Support as Topic MeSH
- Immunohistochemistry methods MeSH
- Models, Animal MeSH
- Rats, Wistar MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
The subvetricular zone is the site for postnatal neurogenesis of interneurons of the olfactory bulb. Concurrently or after proliferation, neuronal precursors therein migrate within it to reach the olfactory bulb, an event known as the rostral migratory stream (RMS). During the first three postnatal weeks remarkable developmental changes are evident in the RMS of rat. The objective of this study was to analyze neurogenesis and cell death in the rat RMS at different stages during the first postnatal months of life. Quantification of proliferating and dying cells showed that the number of these cells in the RMS is dependent on age stage during early postnatal life. We also put evidence that the observed quantitative changes are different in individual parts of the RMS.
Cell proliferation and apoptosis in the rostral migratory stream of developing rats
Bunkové delenie a apoptóza v rostrálnej migračnej dráhe potkana v skorom postnatálnom vývoji = Cell proliferation and apoptosis in the rostral migratory stream of developing rats : 12. Celostátní konference biologické psychiatrie "Teorie a praxe biologické psychiatrie". Luhačovice, 15.-18. června 2005. [Krátká sdělení] /
Cell proliferation and apoptosis in the rostral migratory stream of developing rats : 12. Celostátní konference biologické psychiatrie "Teorie a praxe biologické psychiatrie". Luhačovice, 15.-18. června 2005. [Krátká sdělení] /
Lit. 9
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- $a The subvetricular zone is the site for postnatal neurogenesis of interneurons of the olfactory bulb. Concurrently or after proliferation, neuronal precursors therein migrate within it to reach the olfactory bulb, an event known as the rostral migratory stream (RMS). During the first three postnatal weeks remarkable developmental changes are evident in the RMS of rat. The objective of this study was to analyze neurogenesis and cell death in the rat RMS at different stages during the first postnatal months of life. Quantification of proliferating and dying cells showed that the number of these cells in the RMS is dependent on age stage during early postnatal life. We also put evidence that the observed quantitative changes are different in individual parts of the RMS.
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