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Měření proteomických dat hmotnostní spektrometrií a jejich bioinformatická interpretace
[Acquisition of proteomic data using mass spectrometry and their bioinformatics interpretation]
Pavel Řehulka, Helena Řehulková, Josef Chmelík
Language Czech Country Czech Republic
- MeSH
- Peptide Mapping MeSH
- Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization methods instrumentation MeSH
The review provides a brief overview of techniques used for interpretation of mass spectrometric data acquired in proteomic experiments. Processing of the data by bioinformatics is an important part of protein identification in proteomics. Analyzed samples can be measured using different mass spectrometric techniques and the obtained data require different methods of processing. Genomic databases rapidly grow and a suitable way of manipulation with data becomes a crucial step for their correct interpretation. Basic methods of interpretation of mass spectrometric data are summarized and some examples show how the corresponding programs work.
Acquisition of proteomic data using mass spectrometry and their bioinformatics interpretation
Lit.: 59
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- $a Měření proteomických dat hmotnostní spektrometrií a jejich bioinformatická interpretace / $c Pavel Řehulka, Helena Řehulková, Josef Chmelík
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- $a Acquisition of proteomic data using mass spectrometry and their bioinformatics interpretation
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- $a Ústav analytické chemie Akademie věd ČR, Brno
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- $a Lit.: 59
- 520 9_
- $a The review provides a brief overview of techniques used for interpretation of mass spectrometric data acquired in proteomic experiments. Processing of the data by bioinformatics is an important part of protein identification in proteomics. Analyzed samples can be measured using different mass spectrometric techniques and the obtained data require different methods of processing. Genomic databases rapidly grow and a suitable way of manipulation with data becomes a crucial step for their correct interpretation. Basic methods of interpretation of mass spectrometric data are summarized and some examples show how the corresponding programs work.
- 650 _2
- $a peptidové mapování $7 D010449
- 650 _2
- $a spektrometrie hmotnostní - ionizace laserem za účasti matrice $x metody $x přístrojové vybavení $7 D019032
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- $a Řehulková, Helena. $7 xx0204964
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- $a Chmelík, Josef. $7 _BN001654
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- $w MED00011010 $t Chemické listy $g Roč. 101, č. 4 (2007), s. 279-286 $x 0009-2770
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- $u http://chemicke-listy.vscht.cz/docs/full/2007_04_279-286.pdf $y plný text volně přístupný
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- $a 2007 $b 101 $c 4 $d 279-286 $i 0009-2770 $m Chemické listy $x MED00011010
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- $a 2007-14/mkmv
