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Fibrilace síní a městnavé srdeční selhání
[Atrial fibrillation and congestive heart failure]
Denis Roy, Mario Talajic, Marc Dubuc, Bernard Thibault, Peter Guerra, Laurent Macle, Paul Khairy
Language Czech Country Czech Republic
- MeSH
- Anti-Arrhythmia Agents therapeutic use MeSH
- Anticoagulants therapeutic use MeSH
- Adrenergic beta-Antagonists therapeutic use MeSH
- Digoxin therapeutic use MeSH
- Atrial Fibrillation epidemiology drug therapy complications MeSH
- Cardiomyopathies diagnosis etiology MeSH
- Catheter Ablation MeSH
- Comorbidity MeSH
- Humans MeSH
- Randomized Controlled Trials as Topic MeSH
- Heart Rate MeSH
- Heart Failure epidemiology complications MeSH
- Tachycardia complications MeSH
- Check Tag
- Humans MeSH
The present review will examine the prognostic importance of atrial fibrillation and heart failure, explore the different therapeutic options for treating atrial fibrillation and present the results of the Atrial Fibrillation and Congestive Heart Failure (AF-CHF) trial. RECENT FINDINGS: The Atrial Fibrillation and Congestive Heart Failure trial was a randomized trial involving patients with both atrial fibrillation and heart failure. The trial was designed to compare the maintenance of sinus rhythm with the control of ventricular rate in patients with left ventricular dysfunction, heart failure and a history of atrial fibrillation. There was no significant difference in the rate of death from cardiovascular causes in the rhythm-control group as compared with the rate-control strategy. In addition, there was no significant difference in any of the secondary outcomes including death from any cause, worsening heart failure or stroke. The rate-control strategy eliminated the need for repeated cardioversion and reduced rates of hospitalization. SUMMARY: The results of the Atrial Fibrillation and Congestive Heart Failure trial indicate that a routine strategy of rhythm control does not reduce rate of death and suggest that rate control should be considered a primary approach for patients with atrial fibrillation and heart failure.
Atrial fibrillation and congestive heart failure
Lit.: 70
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- $a Fibrilace síní a městnavé srdeční selhání / $c Denis Roy, Mario Talajic, Marc Dubuc, Bernard Thibault, Peter Guerra, Laurent Macle, Paul Khairy
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- $a Atrial fibrillation and congestive heart failure
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- $a Montreal Heart Institute and Department of Medicine, Université de Montréal, Montreal, Quebec, Canada denis.roy@umontreal.ca
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- $a Lit.: 70
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- $a The present review will examine the prognostic importance of atrial fibrillation and heart failure, explore the different therapeutic options for treating atrial fibrillation and present the results of the Atrial Fibrillation and Congestive Heart Failure (AF-CHF) trial. RECENT FINDINGS: The Atrial Fibrillation and Congestive Heart Failure trial was a randomized trial involving patients with both atrial fibrillation and heart failure. The trial was designed to compare the maintenance of sinus rhythm with the control of ventricular rate in patients with left ventricular dysfunction, heart failure and a history of atrial fibrillation. There was no significant difference in the rate of death from cardiovascular causes in the rhythm-control group as compared with the rate-control strategy. In addition, there was no significant difference in any of the secondary outcomes including death from any cause, worsening heart failure or stroke. The rate-control strategy eliminated the need for repeated cardioversion and reduced rates of hospitalization. SUMMARY: The results of the Atrial Fibrillation and Congestive Heart Failure trial indicate that a routine strategy of rhythm control does not reduce rate of death and suggest that rate control should be considered a primary approach for patients with atrial fibrillation and heart failure.
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