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Synthesis of unsymmetric cyanine dye via merocyanine and their interaction with DNA

Tomáš Bříza, Zdeněk Kejík, Jarmila Králová, Pavel Martásek and Vladimír Král

. 2009 ; 74 (7-8) : 1081-1090.

Jazyk angličtina Země Česko

Perzistentní odkaz   https://www.medvik.cz/link/bmc09004757

An effective method has been developed for synthesis of neutral merocyanine dye 4 from (4-nitrophenyl)malondialdehyde. Merocyanine 4 was used as a basic building block for preparation of unsymmetric cyanine dyes 9 and 10, both derived from the same aromatic malondialdehyde. With the cyanine 10, pH-dependent affinity to DNA has been studied. Unsymmetric cyanine dye 10 has been compared with symmetric dye 8. The corresponding binding constants (K) have been calculated for various pH.

Citace poskytuje Crossref.org

Bibliografie atd.

Lit.: 12

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