Porovnali sme liečebné postupy v dvoch rovnako velkých skupinách pacientov (n = 30) hospitalizovaných s akútnou psychózou na psychiatrických klinikách v Bratislave (BA) a Prahe (PA). Zaznamenávali sme liečbu podanú v prvých troch dňoch po prijatí a v 14. dni hospitalizácie. Medzi terapeutickou praxou v Prahe a Bratislave nenachádzame výrazné odlišnosti. V oboch centrách sú v úvode akútnej liečby najčastejšie využívané antipsychotiká haloperidol, olanzapín a risperidón. V 14. dni liečby je zreteľná tendencia k mono-terapii antipsychotikami. Použité dávky antipsychotík boli nesignifikantne vyššie v Bratislave (chlorpromazínový ekvivalent BA 1167 mg vs. PA 956 mg pre prvé tri dni hospitalizácie a 586 mg in BA vs. 390 mg in PA pre 14. deň hospitalizácie). Pomerne málo sa využila elektrokonvulzívna terapia (4 pacienti). Použitie obmedzovacích prostriedkov v oboch centrách bolo v rovnakej miere - približne u 1/3 pacientov.

The treatment practices were compared in two groups (each group n = 30) of patients with acute psychotic disorder at psychiatric clinics in Prague (PA) and Bratislava (BA). The treatment with psychopharmacological drugs was evaluated for the period of the first three days of hospitalization and for the 14th day of hospitalization. Differences found in treatment practice were not significant. Most frequently used antipsychotics in both centers were haloperidol, olanzapine and risperidone. Average dose of antipsychotics used was non-significantly higher in Bratislava than in Prague (chlorpromazine equivalent of 1167mg in BA vs. 956 mg in PA for the first three days of hospitalization and 586 mg in BA vs. 390 mg in PA for 14th day of hospitalization). Use of electroconvulsive therapy in acute setting was rare. The need for using the restraint was found in approximately one third of patients.

Psychiatrická klinika LF UK a FNsR Bratislava

Probe of psychopharmacological treatment of patients with acute psychosis at Clinic of Psychiatry, Faculty of Medicine, Comenius University in Bratislava and at the Clinic of Psychiatry, 1st Faculty of Medicine, Charles University in Prague

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