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Polymorphisme du microsatellite mitochondrial D310 dans la population Tunisienne
Besma Yacoubi-Loueslati, Lotfi Cherni, Sabeh Frigi, Thouraya Baroudi, Amel Ben Ammar El Gaaied
Jazyk francouzština Země Česko
NLK
ProQuest Central
od 2001-01-01 do Před 1 rokem
ROAD: Directory of Open Access Scholarly Resources
od 1987
- MeSH
- interpretace statistických dat MeSH
- lidé MeSH
- mitochondriální DNA analýza diagnostické užití genetika MeSH
- polymorfismus genetický genetika MeSH
- Check Tag
- lidé MeSH
- Geografické názvy
- Tunisko MeSH
In the present study, we have investigated the polymorphism of the mitochondrial microsatellite, situated between 303 and 315 bp positions, in a Tunisian population. The haplotype frequencies of this microsatellite were compared to those of other populations (Berbers from Sejnene and Takrouna, Bedouins, Portuguese, Italians, French, British, Spanish and Turkish). The obtained results reveal this mitochondrial microsatellite as a frequent hot spot of mononucleotide insertions. In fact, his polymorphic rate is superior to 93% in all analysed populations. The results showed that the two haplotypes 309.1 315.1 and 315.1 are the most frequent in all studied populations. The haplotype corresponding to the Cambridge Reference Sequence (CRS) is only detected in the Tunisian population, the Berbers from Sejnene and the British people.
Lit.: 39
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- $a Département de Biologie Faculté des Sciences de Tunis Université El Manar
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- $a Lit.: 39
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- $a In the present study, we have investigated the polymorphism of the mitochondrial microsatellite, situated between 303 and 315 bp positions, in a Tunisian population. The haplotype frequencies of this microsatellite were compared to those of other populations (Berbers from Sejnene and Takrouna, Bedouins, Portuguese, Italians, French, British, Spanish and Turkish). The obtained results reveal this mitochondrial microsatellite as a frequent hot spot of mononucleotide insertions. In fact, his polymorphic rate is superior to 93% in all analysed populations. The results showed that the two haplotypes 309.1 315.1 and 315.1 are the most frequent in all studied populations. The haplotype corresponding to the Cambridge Reference Sequence (CRS) is only detected in the Tunisian population, the Berbers from Sejnene and the British people.
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