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Polymorphisme du microsatellite mitochondrial D310 dans la population Tunisienne
Besma Yacoubi-Loueslati, Lotfi Cherni, Sabeh Frigi, Thouraya Baroudi, Amel Ben Ammar El Gaaied
Language French Country Czech Republic
NLK
ProQuest Central
from 2001-01-01 to 1 year ago
ROAD: Directory of Open Access Scholarly Resources
from 1987
- MeSH
- Data Interpretation, Statistical MeSH
- Humans MeSH
- DNA, Mitochondrial analysis diagnostic use genetics MeSH
- Polymorphism, Genetic genetics MeSH
- Check Tag
- Humans MeSH
- Geographicals
- Tunisia MeSH
In the present study, we have investigated the polymorphism of the mitochondrial microsatellite, situated between 303 and 315 bp positions, in a Tunisian population. The haplotype frequencies of this microsatellite were compared to those of other populations (Berbers from Sejnene and Takrouna, Bedouins, Portuguese, Italians, French, British, Spanish and Turkish). The obtained results reveal this mitochondrial microsatellite as a frequent hot spot of mononucleotide insertions. In fact, his polymorphic rate is superior to 93% in all analysed populations. The results showed that the two haplotypes 309.1 315.1 and 315.1 are the most frequent in all studied populations. The haplotype corresponding to the Cambridge Reference Sequence (CRS) is only detected in the Tunisian population, the Berbers from Sejnene and the British people.
Lit.: 39
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- $a Yacoubi-Loueslati, Besma
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- $a Polymorphisme du microsatellite mitochondrial D310 dans la population Tunisienne / $c Besma Yacoubi-Loueslati, Lotfi Cherni, Sabeh Frigi, Thouraya Baroudi, Amel Ben Ammar El Gaaied
- 314 __
- $a Département de Biologie Faculté des Sciences de Tunis Université El Manar
- 504 __
- $a Lit.: 39
- 520 9_
- $a In the present study, we have investigated the polymorphism of the mitochondrial microsatellite, situated between 303 and 315 bp positions, in a Tunisian population. The haplotype frequencies of this microsatellite were compared to those of other populations (Berbers from Sejnene and Takrouna, Bedouins, Portuguese, Italians, French, British, Spanish and Turkish). The obtained results reveal this mitochondrial microsatellite as a frequent hot spot of mononucleotide insertions. In fact, his polymorphic rate is superior to 93% in all analysed populations. The results showed that the two haplotypes 309.1 315.1 and 315.1 are the most frequent in all studied populations. The haplotype corresponding to the Cambridge Reference Sequence (CRS) is only detected in the Tunisian population, the Berbers from Sejnene and the British people.
- 650 _2
- $a lidé $7 D006801
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- $a polymorfismus genetický $x genetika $7 D011110
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- $a mitochondriální DNA $x analýza $x diagnostické užití $x genetika $7 D004272
- 650 _2
- $a interpretace statistických dat $7 D003627
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- $a Tunisko $7 D014416
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- $a Frigi, Sabeh
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- $a Baroudi, Thouraya
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- $a El Gaaied, Amel Ben Ammar
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- $w MED00152805 $t Anthropologie $g Roč. 47, č. 1-2 (2009), s. 89-94 $x 0323-1119
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