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www.rnaworkbench.com: A new program for analyzing RNA interference
R. S. Vařeková, I. Bradáč, M. Plchút, M. Škrdla, M. Wacenovsky, H. Mahr, G. Mayer, H. Tanner, H. Brugger, J. Withalm, P. Lederer, H. Huber, G. Gierlinger, R. Graf, H. Tafer, I. Hofacker, P. Schuster, M. Polčík
Jazyk angličtina Země Irsko
- MeSH
- algoritmy MeSH
- financování organizované MeSH
- genový targeting metody MeSH
- malá interferující RNA genetika MeSH
- molekulární sekvence - údaje MeSH
- RNA interference MeSH
- sekvence nukleotidů MeSH
- sekvenční analýza RNA metody MeSH
- sekvenční seřazení metody MeSH
- software MeSH
RNA interference (RNAi) has become an important tool to study and utilize gene silencing by introducing short interfering RNA (siRNA). In order to predict the most efficient siRNAs, a new software tool, RNA Workbench (RNAWB), has been designed and is freely available (after registration) on http://www.rnaworkbench.com. In addition to the standard selection rules, RNAWB includes the possibility of statistical analyses of the applied selection rules (criteria). The role of RNA secondary structures in the RNA interference process as well as the application of sequence rules are discussed to show the applicability of the software.
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- $a RNA interference (RNAi) has become an important tool to study and utilize gene silencing by introducing short interfering RNA (siRNA). In order to predict the most efficient siRNAs, a new software tool, RNA Workbench (RNAWB), has been designed and is freely available (after registration) on http://www.rnaworkbench.com. In addition to the standard selection rules, RNAWB includes the possibility of statistical analyses of the applied selection rules (criteria). The role of RNA secondary structures in the RNA interference process as well as the application of sequence rules are discussed to show the applicability of the software.
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