Detail
Article
Online article
FT
Medvik - BMC
  • Something wrong with this record ?

Cybrid human embryos--warranting opportunities to augment embryonic stem cell research

J Jr Fulka, H Fulka, John J St, C Galli, G Lazzari, I Lagutina, J Fulka, P Loi

. 2008 ; 26 (9) : 469-474.

Language English Country Great Britain

E-resources Online Full text

NLK ProQuest Central from 2002-01-01 to 2 months ago
Health & Medicine (ProQuest) from 2002-01-01 to 2 months ago
Health Management Database (ProQuest) from 2002-01-01 to 2 months ago

The recent vote in the British Parliament allows scientists in principle to create hybrid embryos by transferring human somatic cell nuclei into animal oocytes. This vote opens a fascinating new area of research with the central aim of generating interspecific lines of embryonic stem cells (ESCs) that could potentially be used to understand development, differentiation, gene expression and genomic compatibility. It will also promote human cell therapies, as well as the pharmaceutical industry's search for new drug targets. If this approach is to be successful, many biological questions need to be answered and, in addition, some moral and ethical aspects must be taken into account.

References provided by Crossref.org

000      
02757naa 2200529 a 4500
001      
bmc11006829
003      
CZ-PrNML
005      
20121126122629.0
008      
110406s2008 xxk e eng||
009      
AR
024    __
$a 10.1016/j.tibtech.2008.06.001 $2 doi
035    __
$a (PubMed)18675481
040    __
$a ABA008 $b cze $c ABA008 $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxk
100    1_
$a Fulka, Josef $7 xx0127350
245    10
$a Cybrid human embryos--warranting opportunities to augment embryonic stem cell research / $c J Jr Fulka, H Fulka, John J St, C Galli, G Lazzari, I Lagutina, J Fulka, P Loi
314    __
$a Institute of Animal Science, Prague, Czech Republic. fulka@vuzv.cz
520    9_
$a The recent vote in the British Parliament allows scientists in principle to create hybrid embryos by transferring human somatic cell nuclei into animal oocytes. This vote opens a fascinating new area of research with the central aim of generating interspecific lines of embryonic stem cells (ESCs) that could potentially be used to understand development, differentiation, gene expression and genomic compatibility. It will also promote human cell therapies, as well as the pharmaceutical industry's search for new drug targets. If this approach is to be successful, many biological questions need to be answered and, in addition, some moral and ethical aspects must be taken into account.
650    _2
$a zvířata $7 D000818
650    _2
$a buněčné linie $7 D002460
650    _2
$a klonování organismů $x etika $7 D019976
650    _2
$a nakládání s embryem $x etika $7 D019924
650    _2
$a embryo savčí $x cytologie $x fyziologie $7 D004622
650    _2
$a embryonální kmenové buňky $x cytologie $7 D053595
650    _2
$a lidé $7 D006801
650    _2
$a multipotentní kmenové buňky $x cytologie $x metabolismus $7 D039902
650    _2
$a přeprogramování buněk $x fyziologie $7 D065150
650    _2
$a techniky jaderného přenosu $x etika $x trendy $x zákonodárství a právo $7 D053652
650    _2
$a oocyty $x cytologie $7 D009865
650    _2
$a tvorba embrya pro výzkumné účely $x etika $x metody $x zákonodárství a právo $7 D035845
650    _2
$a totipotentní kmenové buňky $x cytologie $7 D039901
650    _2
$a totipotentní kmenové buňky $x metabolismus $7 D039901
650    _2
$a financování organizované $7 D005381
700    1_
$a Fulková, Helena, $d 1980- $7 xx0107801
700    1_
$a St John, Justin
700    1_
$a Galli, Cesare
700    1_
$a Lazzari, Giovanna
700    1_
$a Lagutina, Irina
700    1_
$a Fulka, Josef, $d 1951- $7 xx0053809
700    1_
$a Loi, Pasqualino
773    0_
$t Trends in Biotechnology $w MED00004563 $g Roč. 26, č. 9 (2008), s. 469-474 $x 0167-7799
910    __
$a ABA008 $b x $y 7
990    __
$a 20110412131204 $b ABA008
991    __
$a 20121126122655 $b ABA008
999    __
$a ok $b bmc $g 834446 $s 698948
BAS    __
$a 3
BMC    __
$a 2008 $b 26 $c 9 $d 469-474 $i 0167-7799 $m Trends in biotechnology $n Trends Biotechnol $x MED00004563
LZP    __
$a 2011-4B/ewme

Find record

Citation metrics

Loading data ...

Archiving options

Loading data ...