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The role of hydrogen peroxide and other reactive oxygen species in wound healing
Jiří Kanta
Language English Country Czech Republic
Document type Review
Digital library NLK
Full text - Article
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NLK
Directory of Open Access Journals
from 1997
Free Medical Journals
from 1997
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from 1997-01-01
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- MeSH
- Financing, Organized MeSH
- Granulation Tissue cytology chemistry MeSH
- Wound Healing physiology MeSH
- Hyperbaric Oxygenation utilization MeSH
- Hypoxia physiopathology MeSH
- Humans MeSH
- Peroxides pharmacology therapeutic use MeSH
- Reactive Oxygen Species pharmacology metabolism MeSH
- Check Tag
- Humans MeSH
- Publication type
- Review MeSH
Wound healing is a complex physiological process important for tissue homeostasis. An acute injury initiates massive cell migration, proliferation and differentiation, synthesis of extracellular matrix components, scar formation and remodelling. Blood flow and tissue oxygenation are parts of the complex regulation of healing. Higher organisms utilize molecular oxygen as a terminal oxidant. This way of gaining energy for vital processes such as healing leads to the production of a number of oxygen compounds that may have a defensive or informatory role. They may be harmful when present in high concentrations. Both the lack and the excess of reactive oxygen species may influence healing negatively.
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Obsahuje 1 tabulku
Bibliography, etc.Literatura
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- $a Wound healing is a complex physiological process important for tissue homeostasis. An acute injury initiates massive cell migration, proliferation and differentiation, synthesis of extracellular matrix components, scar formation and remodelling. Blood flow and tissue oxygenation are parts of the complex regulation of healing. Higher organisms utilize molecular oxygen as a terminal oxidant. This way of gaining energy for vital processes such as healing leads to the production of a number of oxygen compounds that may have a defensive or informatory role. They may be harmful when present in high concentrations. Both the lack and the excess of reactive oxygen species may influence healing negatively.
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