-
Je něco špatně v tomto záznamu ?
Phenolic compounds from Allium schoenoprasum, Tragopogon pratensis and Rumex acetosa and their antiproliferative effects
Z. Kucekova, J. Mlcek, P. Humpolicek, O. Rop, P. Valasek, P. Saha,
Jazyk angličtina Země Švýcarsko
Typ dokumentu časopisecké články, práce podpořená grantem
Free Medical Journals od 1997
PubMed Central od 2001
Europe PubMed Central od 2001
ProQuest Central od 1997-01-01
Open Access Digital Library od 1997-01-01
Medline Complete (EBSCOhost) od 2009-03-01
Health & Medicine (ProQuest) od 1997-01-01
Odkazy
PubMed
22051932
DOI
10.3390/molecules16119207
Knihovny.cz E-zdroje
- MeSH
- antitumorózní látky chemie farmakologie MeSH
- fenoly chemie farmakologie MeSH
- květy chemie MeSH
- léky antitumorózní - screeningové testy MeSH
- lidé MeSH
- nádorové buněčné linie účinky léků MeSH
- pažitka anatomie a histologie chemie MeSH
- rostlinné extrakty chemie farmakologie MeSH
- Rumex anatomie a histologie chemie MeSH
- Tragopogon anatomie a histologie chemie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
Experimental studies have shown that phenolic compounds have antiproliferative and tumour arresting effects. The aim of this original study was to investigate the content of phenolic compounds (PhC) in flowers of Allium schoenoprasum (chive), Tragopogon pratensis (meadow salsify) and Rumex acetosa (common sorrel) and their effect on proliferation of HaCaT cells. Antiproliferative effects were evaluated in vitro using the following concentrations of phenolic compounds in cultivation medium: 100, 75, 50 and 25 µg/mL. Phenolic composition was also determined by HPLC. The results indicate that even low concentrations of these flowers' phenolic compounds inhibited cell proliferation significantly and the possible use of the studied herb's flowers as sources of active phenolic compounds for human nutrition.
- 000
- 00000naa a2200000 a 4500
- 001
- bmc12024302
- 003
- CZ-PrNML
- 005
- 20121207123620.0
- 007
- ta
- 008
- 120815e20111103sz f 000 0#eng||
- 009
- AR
- 024 7_
- $a 10.3390/molecules16119207 $2 doi
- 035 __
- $a (PubMed)22051932
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a sz
- 100 1_
- $a Kucekova, Zdenka $u Polymer Centre, Faculty of Technology, Tomas Bata University at Zlin, 76272 Zlin, Czech Republic.
- 245 10
- $a Phenolic compounds from Allium schoenoprasum, Tragopogon pratensis and Rumex acetosa and their antiproliferative effects / $c Z. Kucekova, J. Mlcek, P. Humpolicek, O. Rop, P. Valasek, P. Saha,
- 520 9_
- $a Experimental studies have shown that phenolic compounds have antiproliferative and tumour arresting effects. The aim of this original study was to investigate the content of phenolic compounds (PhC) in flowers of Allium schoenoprasum (chive), Tragopogon pratensis (meadow salsify) and Rumex acetosa (common sorrel) and their effect on proliferation of HaCaT cells. Antiproliferative effects were evaluated in vitro using the following concentrations of phenolic compounds in cultivation medium: 100, 75, 50 and 25 µg/mL. Phenolic composition was also determined by HPLC. The results indicate that even low concentrations of these flowers' phenolic compounds inhibited cell proliferation significantly and the possible use of the studied herb's flowers as sources of active phenolic compounds for human nutrition.
- 650 _2
- $a antitumorózní látky $x chemie $x farmakologie $7 D000970
- 650 _2
- $a nádorové buněčné linie $x účinky léků $7 D045744
- 650 _2
- $a pažitka $x anatomie a histologie $x chemie $7 D027782
- 650 _2
- $a léky antitumorózní - screeningové testy $7 D004354
- 650 _2
- $a květy $x chemie $7 D035264
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a fenoly $x chemie $x farmakologie $7 D010636
- 650 _2
- $a rostlinné extrakty $x chemie $x farmakologie $7 D010936
- 650 _2
- $a Rumex $x anatomie a histologie $x chemie $7 D031804
- 650 _2
- $a Tragopogon $x anatomie a histologie $x chemie $7 D031188
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a práce podpořená grantem $7 D013485
- 700 1_
- $a Mlcek, Jiri
- 700 1_
- $a Humpolicek, Petr
- 700 1_
- $a Rop, Otakar
- 700 1_
- $a Valasek, Pavel
- 700 1_
- $a Saha, Petr
- 773 0_
- $w MED00180394 $t Molecules (Basel, Switzerland) $x 1420-3049 $g Roč. 16, č. 11 (20111103), s. 9207-17
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/22051932 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y m
- 990 __
- $a 20120815 $b ABA008
- 991 __
- $a 20121207123654 $b ABA008
- 999 __
- $a ok $b bmc $g 946450 $s 781630
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2011 $b 16 $c 11 $d 9207-17 $e 20111103 $i 1420-3049 $m Molecules $n Molecules $x MED00180394
- LZP __
- $a Pubmed-20120815/12/02