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Supersaturation of body fluids, plasma and urine, with respect to biological hydroxyapatite
O. Söhnel, F. Grases
Jazyk angličtina Země Německo
Typ dokumentu časopisecké články
- MeSH
- biologické modely MeSH
- fosfáty krev moč MeSH
- hydroxyapatit krev moč MeSH
- koncentrace vodíkových iontů MeSH
- lidé MeSH
- tělesné tekutiny metabolismus MeSH
- vápník krev moč MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
Supersaturation of body fluids, specifically of plasma and urine, with respect to biological hydroxyapatite was evaluated taking into account calcium complexation, fraction of total phosphorus present as hydrogen phosphate ions, solubility of carbonated hydroxyapatite and the size dependency of equilibrium solubility. Plasma is always supersaturated with respect to apatitic solid phase and thus calcific deposits are formed unless a sufficient quantity of potent inhibitors is present. When urinary pH is lower than 6.3 for normal urine hydroxyapatite cannot appear in renal stones, at higher pH apatitic renal stones can be formed. Predictions based on supersaturation calculated for different conditions correspond well with clinical observations.
Faculty of Enviromental Studies University of J E Purkyne Usti n L Czech Republic
University Institute of Health Sciences Research University of Illes Balears Palma de Mallorca Spain
Citace poskytuje Crossref.org
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