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New antioxidant flavonoid isolated from Leuzea carthamoides
V. Koleckar, L. Opletal, K. Macakova, L. Jahodar, D. Jun, J. Kunes, K. Kuca
Language English Country England, Great Britain
Document type Journal Article, Research Support, Non-U.S. Gov't
NLK
Taylor & Francis Open Access
from 2002-01-01
Medline Complete (EBSCOhost)
from 2007-02-01
- MeSH
- Antioxidants chemistry isolation & purification pharmacology MeSH
- Flavonoids chemistry isolation & purification pharmacology MeSH
- Spectrometry, Mass, Electrospray Ionization MeSH
- Leuzea chemistry MeSH
- Magnetic Resonance Spectroscopy MeSH
- Spectrophotometry, Ultraviolet MeSH
- Structure-Activity Relationship MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
A new natural flavonoid patuletin 3'-beta-xylofuranoside was isolated from Leuzea carthamoides leaves. The antioxidant activity of this compound was evaluated by the DPPH radical assay and ferric reducing antioxidant power (FRAP) assay, and the results were compared with those for trolox and quercetin. DPPH radical scavenging activity of the tested compounds was expressed by the parameter EC50: patuletin 3'-beta-xylofuranoside (56.0 microM), trolox (27.8 microM), and quercetin (25.3 microM). The ferric reducing activity of the compounds was demonstrated as FRAP values at 4 and 60 min: patuletin 3'-beta-xylofuranoside (28.4 microM, 35.8 microM), trolox (19.3 microM, 20.2 microM), and quercetin (54.3 microM, 79.9 microM). The structure/activity relationship of the flavonoid is also discussed. The results indicate significant antioxidant potency of patuletin 3'-beta-xylofuranoside.
References provided by Crossref.org
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- $a A new natural flavonoid patuletin 3'-beta-xylofuranoside was isolated from Leuzea carthamoides leaves. The antioxidant activity of this compound was evaluated by the DPPH radical assay and ferric reducing antioxidant power (FRAP) assay, and the results were compared with those for trolox and quercetin. DPPH radical scavenging activity of the tested compounds was expressed by the parameter EC50: patuletin 3'-beta-xylofuranoside (56.0 microM), trolox (27.8 microM), and quercetin (25.3 microM). The ferric reducing activity of the compounds was demonstrated as FRAP values at 4 and 60 min: patuletin 3'-beta-xylofuranoside (28.4 microM, 35.8 microM), trolox (19.3 microM, 20.2 microM), and quercetin (54.3 microM, 79.9 microM). The structure/activity relationship of the flavonoid is also discussed. The results indicate significant antioxidant potency of patuletin 3'-beta-xylofuranoside.
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