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New antioxidant flavonoid isolated from Leuzea carthamoides
V. Koleckar, L. Opletal, K. Macakova, L. Jahodar, D. Jun, J. Kunes, K. Kuca
Jazyk angličtina Země Anglie, Velká Británie
Typ dokumentu časopisecké články, práce podpořená grantem
NLK
Taylor & Francis Open Access
od 2002-01-01
Medline Complete (EBSCOhost)
od 2007-02-01
- MeSH
- antioxidancia chemie izolace a purifikace farmakologie MeSH
- flavonoidy chemie izolace a purifikace farmakologie MeSH
- hmotnostní spektrometrie s elektrosprejovou ionizací MeSH
- Leuzea chemie MeSH
- magnetická rezonanční spektroskopie MeSH
- spektrofotometrie ultrafialová MeSH
- vztahy mezi strukturou a aktivitou MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
A new natural flavonoid patuletin 3'-beta-xylofuranoside was isolated from Leuzea carthamoides leaves. The antioxidant activity of this compound was evaluated by the DPPH radical assay and ferric reducing antioxidant power (FRAP) assay, and the results were compared with those for trolox and quercetin. DPPH radical scavenging activity of the tested compounds was expressed by the parameter EC50: patuletin 3'-beta-xylofuranoside (56.0 microM), trolox (27.8 microM), and quercetin (25.3 microM). The ferric reducing activity of the compounds was demonstrated as FRAP values at 4 and 60 min: patuletin 3'-beta-xylofuranoside (28.4 microM, 35.8 microM), trolox (19.3 microM, 20.2 microM), and quercetin (54.3 microM, 79.9 microM). The structure/activity relationship of the flavonoid is also discussed. The results indicate significant antioxidant potency of patuletin 3'-beta-xylofuranoside.
Citace poskytuje Crossref.org
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- $a A new natural flavonoid patuletin 3'-beta-xylofuranoside was isolated from Leuzea carthamoides leaves. The antioxidant activity of this compound was evaluated by the DPPH radical assay and ferric reducing antioxidant power (FRAP) assay, and the results were compared with those for trolox and quercetin. DPPH radical scavenging activity of the tested compounds was expressed by the parameter EC50: patuletin 3'-beta-xylofuranoside (56.0 microM), trolox (27.8 microM), and quercetin (25.3 microM). The ferric reducing activity of the compounds was demonstrated as FRAP values at 4 and 60 min: patuletin 3'-beta-xylofuranoside (28.4 microM, 35.8 microM), trolox (19.3 microM, 20.2 microM), and quercetin (54.3 microM, 79.9 microM). The structure/activity relationship of the flavonoid is also discussed. The results indicate significant antioxidant potency of patuletin 3'-beta-xylofuranoside.
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