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Evaluation of the antiradical activity of Schisandra chinensis lignans using different experimental models
K. Smejkal, T. Slapetová, P. Krmencík, R. Kubínová, P. Suchý, S. Dall'Acqua, G. Innocenti, J. Vanco, K. Kalvarová, M. Dvorská, J. Slanina, E. Kramárová, J. Muselík, M. Zemlicka,
Jazyk angličtina Země Švýcarsko
Typ dokumentu časopisecké články, práce podpořená grantem
NLK
Directory of Open Access Journals
od 1997
Free Medical Journals
od 1997
PubMed Central
od 2001
Europe PubMed Central
od 2001
ProQuest Central
od 1997-01-01
Open Access Digital Library
od 1997-01-01
Medline Complete (EBSCOhost)
od 2009-03-01
Health & Medicine (ProQuest)
od 1997-01-01
- MeSH
- antioxidancia farmakologie MeSH
- lignany farmakologie MeSH
- modely u zvířat MeSH
- myši inbrední ICR MeSH
- myši MeSH
- rostlinné extrakty farmakologie MeSH
- scavengery volných radikálů farmakologie MeSH
- Schisandra chemie MeSH
- vysokoúčinná kapalinová chromatografie MeSH
- zvířata MeSH
- Check Tag
- myši MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
The in vitro antiradical activity of Schisandra chinensis lignans was investigated using DPPH, ABTS+, Fenton reaction inhibition and tyrosine-nitration inhibition assays, as were the in vivo antidiabetic activities of selected lignans in an animal model of alloxan-induced diabetes. Different degrees of antiradical activity were found, depending upon the structural parameters of the tested compounds. Unfortunately, the compounds showed no antidiabetic activity in concentration range tested.
Citace poskytuje Crossref.org
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