• Je něco špatně v tomto záznamu ?

Do we need new antibiotics? The search for new targets and new compounds

J. Spížek, J. Novotná, T. Rezanka, AL. Demain

. 2010 ; 37 (12) : 1241-1248. [pub] 20101118

Jazyk angličtina Země Anglie, Velká Británie

Typ dokumentu časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/bmc12026650

Resistance to antibiotics and other antimicrobial compounds continues to increase. There are several possibilities for protection against pathogenic microorganisms, for instance, preparation of new vaccines against resistant bacterial strains, use of specific bacteriophages, and searching for new antibiotics. The antibiotic search includes: (1) looking for new antibiotics from nontraditional or less traditional sources, (2) sequencing microbial genomes with the aim of finding genes specifying biosynthesis of antibiotics, (3) analyzing DNA from the environment (metagenomics), (4) re-examining forgotten natural compounds and products of their transformations, and (5) investigating new antibiotic targets in pathogenic bacteria.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc12026650
003      
CZ-PrNML
005      
20160305113928.0
007      
ta
008      
120816s2010 enk f 000 0#eng||
009      
AR
024    7_
$a 10.1007/s10295-010-0849-8 $2 doi
035    __
$a (PubMed)21086099
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a enk
100    1_
$a Spížek, Jaroslav, $d 1935- $7 jn20000710582 $u Institute of Microbiology, Academy of Sciences of the Czech Republic, Vídeňská 1083, 14220 Prague 4, Czech Republic
245    10
$a Do we need new antibiotics? The search for new targets and new compounds / $c J. Spížek, J. Novotná, T. Rezanka, AL. Demain
520    9_
$a Resistance to antibiotics and other antimicrobial compounds continues to increase. There are several possibilities for protection against pathogenic microorganisms, for instance, preparation of new vaccines against resistant bacterial strains, use of specific bacteriophages, and searching for new antibiotics. The antibiotic search includes: (1) looking for new antibiotics from nontraditional or less traditional sources, (2) sequencing microbial genomes with the aim of finding genes specifying biosynthesis of antibiotics, (3) analyzing DNA from the environment (metagenomics), (4) re-examining forgotten natural compounds and products of their transformations, and (5) investigating new antibiotic targets in pathogenic bacteria.
650    _2
$a antibakteriální látky $x farmakologie $7 D000900
650    _2
$a Bacteria $x účinky léků $x genetika $7 D001419
650    _2
$a bakteriální infekce $x prevence a kontrola $7 D001424
650    _2
$a biologické přípravky $x farmakologie $7 D001688
650    _2
$a bakteriální léková rezistence $x genetika $7 D024881
650    _2
$a genom bakteriální $7 D016680
650    _2
$a metagenomika $7 D056186
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Novotná, Jitka $7 xx0079412 $u Pharmaceutical Institute, University of Tübingen, Auf der Morgenstelle 8, 72076, Tübingen, Germany. jinov1@mail.muni.cz
700    1_
$a Řezanka, Tomáš $7 xx0106317 $u Institute of Microbiology, Academy of Sciences of the Czech Republic
700    1_
$a Demain, A. L. $q (Arnold L.), $d 1927- $7 nlk20040155721 $u Research Institute for Scientists Emeriti (R.I.S.E.), Drew University, Madison, NJ, 07940, USA, ademain@drew.edu
773    0_
$w MED00008013 $t Journal of industrial microbiology & biotechnology $x 1476-5535 $g Roč. 37, č. 12 (2010), s. 1241-1248
856    41
$u https://pubmed.ncbi.nlm.nih.gov/21086099 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y m $z 0
990    __
$a 20120816 $b ABA008
991    __
$a 20160305113941 $b ABA008
999    __
$a ok $b bmc $g 948692 $s 783996
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2010 $b 37 $c 12 $d 1241-1248 $e 20101118 $i 1476-5535 $m Journal of industrial microbiology and biotechnology $n J Ind Microbiol Biotechnol $x MED00008013
LZP    __
$b NLK122 $a Pubmed-20120816/11/01

Najít záznam

Citační ukazatele

Možnosti archivace